volume 55, issue 6, P1546-1554 1990
DOI: 10.1135/cccc19901546
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Abstract: 20-Iodoeicosanoic acid (X) was prepared in 9 steps, its carbon chain being constructed from thiophene and ethyl ester chlorides of dodecanedioic and butanedioic acids. Isotope exchange afforded 20-[125I]-iodoeicosanoic acid required for scintigraphic studies of the myocardium. Desulfuration of the thiophene precursor VIII was accompanied by formation of side products XI-XIX arising by cleavage of the thiophene C-C bonds. Desulfuration of the model compounds XX and XXI has shown that the formation of these prod…

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