volume 12, issue 1, P37-44 2021
DOI: 10.5155/eurjchem.12.1.37-44.2038
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Santhosha Sangapurada Mahantheshappa, Harishkumar Shivanna, Nayak Devappa Satyanarayan

Abstract: The synthesis, antimicrobial, and antioxidant activities of new quinoline analogs were carried out with the aim to find possible hits/leads that can be taken up for future drug development. A series of 2-amino-N’-((2-chloroquinolin-3-yl)methylene)acetohydrazide derivatives (6a-h) have been synthesized by reacting 2-chloro-N’-((2-chloroquinolin-3-yl)methylene)acetohydrazide (5a) and N’-((6-bromo-2-chloroquinolin-3-yl)methylene)-2-chloroacetohydrazide (5b) with secondary amines (Morpholine, diethylamine, piperid…

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