Synthesis and physicochemical characteristics of Nickel (II), Copper (II), Zinc (II), Cadmium (II) and Tin (II) complexes of schiff base with 1, 2, 4-triazole

Abstract

The extreme efforts have been developed to design novel compounds to strains of resistant microorganisms. On-going search for novel and amazing drug delivery systems is primarily impact of the wellestablished fact that the convectional dosages are not sufficiently effective in conveying the drug compounds to its site of action and this has required the need to search for more efficient drugs. New five metal complexes of Nickel(II), Copper(II), Zinc(II), Cadmium(II) and Tin(II) with Schiff base ligand 4-(Benzylidene-amino)-5-pyridin-4-yl-4H-[1,2,4] triazole-3-thiol were synthesized in ethyl alcohol as a solvent. The Synthesized compounds were characterized by different physicochemical techniques such as, elemental analysis C.H.N.S, FT-IR, UVvisible spectrophotometry, 1 H NMR, conductivity and magnetic susceptibility measurements melting point, flame atomic absorption. The Schiff base ligand act as bidentate and coordinated to the metal atoms via the azomethine-N and S atom of thiol group. From the spectral studies, square planar geometry was proposed for the copper complex. The other complexes were proposed to be tetrahedral.