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Cited by 86 publications
(103 citation statements)
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“…Quenching by the pyrimidines appears to be energetically less favorable, and perhaps competing quenching pathways dominate. Our thermodynamic data are consistent with what has been reported for all PTERs when they are incorporated in single-and doublestranded DNA, 18,20 with the exception of 6MI. 24,49 Generally, the FBAs showed the greatest quenching by purine monophosphates, even when complexation was taken into account.…”
Section: Steady-state Fluorescence Quenching Of Fbassupporting
confidence: 94%
See 1 more Smart Citation
“…Quenching by the pyrimidines appears to be energetically less favorable, and perhaps competing quenching pathways dominate. Our thermodynamic data are consistent with what has been reported for all PTERs when they are incorporated in single-and doublestranded DNA, 18,20 with the exception of 6MI. 24,49 Generally, the FBAs showed the greatest quenching by purine monophosphates, even when complexation was taken into account.…”
Section: Steady-state Fluorescence Quenching Of Fbassupporting
confidence: 94%
“…7,18,20,24 These include the adenosine analogue 6MAP and its dimethyl form DMAP and the guanosine analogues 3MI and 6MI. The molecules are highly fluorescent as monomers but quench to varying degrees upon base stacking.…”
Section: Introductionmentioning
confidence: 99%
“…One issue is its relatively low fluorescence quantum yield, about 0.39 for the monomer. 12 This is smaller as compared to other useful probes. For example, FMN has a quantum yield of about 0.6.…”
Section: Discussionmentioning
confidence: 90%
“…The compositions were adenosine and guanosine analogs in which the natural bases were replaced by pteridine nucleoside analogs, capable of acting as hybridization probes for the study of strand interactions. [11][12][13] These syntheses, of probes termed 6-MAP, 3-MI, and 6-MI, are long and require up to 15 reaction steps before reaching the final product. As of December 2006, two of the three ͑6-MAP and 3-MI͒ have been completed.…”
Section: Resultsmentioning
confidence: 99%