Synthesis and characterization of tetrafunctional lactic acid oligomers: A potentialin situ forming degradable orthopaedic biomaterial

Synthesis, Characterization and Cytocompatibility of a Poly(diol-tricarballylate) Visible Light Photo-Cross-Linked Biodegradable Elastomer

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Synthesis, Characterization and Cytocompatibility of a Poly(diol-tricarballylate) Visible Light Photo-Cross-Linked Biodegradable Elastomer

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Photopolymerized Injectable RGD‐Modified Fumarated Poly(ethylene glycol) Diglycidyl Ether Hydrogels for Cell Growth

“…Degradable biomaterials are essential in orthopaedic applications because second surgical intervention is not necessary to remove the implant after a certain time 8. In several studies, it has been reported that the degradation of the hydrogels could be measured by weighing the swollen hydrogels in PBS at a certain time 5, 7, 8. Anseth et al7 synthesized a degradable and photocrosslinkable hydrogel scaffold based on PVA and emphasized that during degradation, hydrogels slowly hydrolyzed and the structure of the network dramatically changed.…”

“…It is clearly seen that the values increase in order. As it is well known, the crosslinking density and heterogeneities such as cyclization, unreacted oligomers, and trapped radicals significantly affect the mechanical properties of the hydrogels 8. The hydrogel with 40 wt.‐% PEGDA (FPEG40‐2) has an elastic modulus almost five times greater than that with 20 wt.‐% PEGDA (FPEG20‐2).…”

Synthesis and Characterization of Star-Shaped Poly(l-lactide)s Initiated with Hydroxyl-Terminated Poly(Amidoamine) (PAMAM-OH) Dendrimers

“…Gaining control over crystallinity has attracted much attention, as the mechanical properties and degradation rates of biodegradable polymers strongly depend on their morphology or crystallinity as well as their chemical structures. For polylactide, the crystallinity is relative to many factors such as thermal history (e.g., annealing), molecular weight, copolymerization, orientation, blending, and stereosequence (e.g., S-length distribution). 1b, Among them, annealing of polylactide at temperatures above T g is considered to be a promising way to achieve control over the degree of crystallinity. 14d, In this study, effects of annealing at 80 °C on crystallinity were investigated.…”

“…In addition to DSC, FTIR, and solid-state NMR techniques, 14d,, WAXS is an effective approach to investigate the crystallinity of PLLA. 1f, From the results presented in Figure , the degree of crystallinity can be obtained by the peak separation of crystalline and amorphous areas. As shown in Table , the crystallinity results obtained by WAXS are in good agreement with DSC results.…”

Synthesis, Characterization and Cytocompatibility of a Poly(diol-tricarballylate) Visible Light Photo-Cross-Linked Biodegradable Elastomer

“……”

Photopolymerized Injectable RGD‐Modified Fumarated Poly(ethylene glycol) Diglycidyl Ether Hydrogels for Cell Growth

“…Degradable biomaterials are essential in orthopaedic applications because second surgical intervention is not necessary to remove the implant after a certain time 8. In several studies, it has been reported that the degradation of the hydrogels could be measured by weighing the swollen hydrogels in PBS at a certain time 5, 7, 8. Anseth et al7 synthesized a degradable and photocrosslinkable hydrogel scaffold based on PVA and emphasized that during degradation, hydrogels slowly hydrolyzed and the structure of the network dramatically changed.…”

“…It is clearly seen that the values increase in order. As it is well known, the crosslinking density and heterogeneities such as cyclization, unreacted oligomers, and trapped radicals significantly affect the mechanical properties of the hydrogels 8. The hydrogel with 40 wt.‐% PEGDA (FPEG40‐2) has an elastic modulus almost five times greater than that with 20 wt.‐% PEGDA (FPEG20‐2).…”

Synthesis and Characterization of Star-Shaped Poly(l-lactide)s Initiated with Hydroxyl-Terminated Poly(Amidoamine) (PAMAM-OH) Dendrimers

“…Gaining control over crystallinity has attracted much attention, as the mechanical properties and degradation rates of biodegradable polymers strongly depend on their morphology or crystallinity as well as their chemical structures. For polylactide, the crystallinity is relative to many factors such as thermal history (e.g., annealing), molecular weight, copolymerization, orientation, blending, and stereosequence (e.g., S-length distribution). 1b, Among them, annealing of polylactide at temperatures above T g is considered to be a promising way to achieve control over the degree of crystallinity. 14d, In this study, effects of annealing at 80 °C on crystallinity were investigated.…”

“…In addition to DSC, FTIR, and solid-state NMR techniques, 14d,, WAXS is an effective approach to investigate the crystallinity of PLLA. 1f, From the results presented in Figure , the degree of crystallinity can be obtained by the peak separation of crystalline and amorphous areas. As shown in Table , the crystallinity results obtained by WAXS are in good agreement with DSC results.…”

Synthesis, Characterization and Cytocompatibility of a Poly(diol-tricarballylate) Visible Light Photo-Cross-Linked Biodegradable Elastomer

“……”

Photopolymerized Injectable RGD‐Modified Fumarated Poly(ethylene glycol) Diglycidyl Ether Hydrogels for Cell Growth

“…Degradable biomaterials are essential in orthopaedic applications because second surgical intervention is not necessary to remove the implant after a certain time 8. In several studies, it has been reported that the degradation of the hydrogels could be measured by weighing the swollen hydrogels in PBS at a certain time 5, 7, 8. Anseth et al7 synthesized a degradable and photocrosslinkable hydrogel scaffold based on PVA and emphasized that during degradation, hydrogels slowly hydrolyzed and the structure of the network dramatically changed.…”

“…It is clearly seen that the values increase in order. As it is well known, the crosslinking density and heterogeneities such as cyclization, unreacted oligomers, and trapped radicals significantly affect the mechanical properties of the hydrogels 8. The hydrogel with 40 wt.‐% PEGDA (FPEG40‐2) has an elastic modulus almost five times greater than that with 20 wt.‐% PEGDA (FPEG20‐2).…”

Synthesis and Characterization of Star-Shaped Poly(l-lactide)s Initiated with Hydroxyl-Terminated Poly(Amidoamine) (PAMAM-OH) Dendrimers

“…Gaining control over crystallinity has attracted much attention, as the mechanical properties and degradation rates of biodegradable polymers strongly depend on their morphology or crystallinity as well as their chemical structures. For polylactide, the crystallinity is relative to many factors such as thermal history (e.g., annealing), molecular weight, copolymerization, orientation, blending, and stereosequence (e.g., S-length distribution). 1b, Among them, annealing of polylactide at temperatures above T g is considered to be a promising way to achieve control over the degree of crystallinity. 14d, In this study, effects of annealing at 80 °C on crystallinity were investigated.…”

“…In addition to DSC, FTIR, and solid-state NMR techniques, 14d,, WAXS is an effective approach to investigate the crystallinity of PLLA. 1f, From the results presented in Figure , the degree of crystallinity can be obtained by the peak separation of crystalline and amorphous areas. As shown in Table , the crystallinity results obtained by WAXS are in good agreement with DSC results.…”