2009
DOI: 10.4028/www.scientific.net/kem.415.49
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Florina Dumitru, Maria Giurginca, O. Micu, C. Guran, Anca Razvan, Nicoleta Maria Badea

Abstract: Chlorhexidine, 1,1'-hexamethylene-bis-[5-(p-chlorophenyl)-biguanide] is a clinically used antiseptic agent with a broad activity spectrum, effective against either Gram positive bacteria such as Mutans streptococcus or Gram negative bacteria such as Pseudomonas aeruginosa. It has eliminating effects on some mycobacteria. In order to prevent the loss of the biological activity caused by poor solubility of chlorhexidine and to limit the side effects of chlorhexidine when used as antiseptic, we synthesised Zn(II)…

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