Synthesis and characterization of pharmacologically active 18-membered tetraamide macrocyclic complexes of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II): <i>In vitro</i> antimicrobial, anticancer screening, DNA interaction and docking studies

Shakir, Mohammad; Bano, Nausheen; Rauf, Ahmar; Kazmi, Shadab; Alam, Mahboob

doi:10.1080/15533174.2016.1186091

Cited by 7 publications

(1 citation statement)

References 54 publications

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“…The broadness of this band confirmed the presence of the Jahn–Teller distortion. 51 The magnetic moment of the C1 complex was found to be 1.92 B.M, suggesting a distorted octahedral geometry around the Cu( ii ) ion. A moderate intense band at 438 nm was attributed to ligand-to-metal charge transfer transition.…”

Section: Resultsmentioning

confidence: 95%

Heteroleptic cobalt complex augments antifungal activity with fluconazole and causes membrane disruption in Candida albicans

Dar,

Hashmi,

Al-Bogami

et al. 2024

Dalton Trans.

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Section: Resultsmentioning

confidence: 95%

Heteroleptic cobalt complex augments antifungal activity with fluconazole and causes membrane disruption in Candida albicans

Dar,

Hashmi,

Al-Bogami

et al. 2024

Dalton Trans.

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Biological Applications of Macrocyclic Schiff Base Ligands and Their Metal Complexes: A Survey of the Literature (2005–2019)

Golbedaghi

Tabanez

Esmaeili

et al. 2020

Applied Organom Chemis

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This article aims to provide a survey of biological applications of Schiff base macrocycles and their metal complexes, with emphasis given to the synthesis of the compounds and to their uses as antibacterial and antifungal agents. The literature on the subject, published during the 2005–2019 period, is shortly reviewed. This is an informed report collecting information on the addressed topic in a concise systematic way, and can be expected to be useful as a fast literature catalogue for researchers working on this and related domains.

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In‐vitro DNA binding and antimicrobial studies of trivalent transition metal ion based macrocyclic complexes

Sangwan

Singh

2019

Vietnam Journal of Chemistry

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In the current research work diaminotoluene based tetra-azamacrocyclic-14 membered [N4] macrocylic complexes of nitrate, chloride and acetate trivalent transition metals salts of Cr(III) and Fe(III) have been synthesized by taking the route of template methodology. The synthesized complexes were fully characterized by spectroscopic and physicoanalytical techniques like IR, ESI-MS, ESR, Powder XRD, TGA, UV-visible, magnetic moment, molar conductance, in addition to the elemental analysis measurements. The monomeric and electrolytic nature of the complexes is elucidated by the help of ESI-MS and molar conductance values that reveals about the 1:2 electrolytic behaviour. On the basis of above analytical techniques the complexes may be empirically formulated as [MLX]X2 in which L is macrocyclic ligand obtained from the [2+2] condensation reaction of 3,4-diaminotoluene (DAT) and dibenzoylmethane (DBM). The thermal data provides an indication towards the absence of water molecular and various decomposition steps in the complexes. Further the compounds were screened for their antimicrobial potency against few strains of bacteria and fungus and fair results were found from the above studies. In addition to these DNA binding activity was also performed in order to elucidate the mode of binding the newly synthesised complexes.

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Synthesis and characterization of pharmacologically active 18-membered tetraamide macrocyclic complexes of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II): In vitro antimicrobial, anticancer screening, DNA interaction and docking studies

Cited by 7 publications

References 54 publications

Heteroleptic cobalt complex augments antifungal activity with fluconazole and causes membrane disruption in Candida albicans

Heteroleptic cobalt complex augments antifungal activity with fluconazole and causes membrane disruption in Candida albicans

Biological Applications of Macrocyclic Schiff Base Ligands and Their Metal Complexes: A Survey of the Literature (2005–2019)

In‐vitro DNA binding and antimicrobial studies of trivalent transition metal ion based macrocyclic complexes

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