Synthesis and characterization of copper(I) derivatives with N-donor ligands—III. Hydridotris (1H-pyrazol-1-yl)borate. The X-ray crystal structure of [HB-(μ-pz)3-Cu(PPh3)]

In Vitroandin VivoAnticancer Activity of Copper(I) Complexes with Homoscorpionate Tridentate Tris(pyrazolyl)borate and Auxiliary Monodentate Phosphine Ligands

“…Characterization of this compound is in agreement with data already reported in the literature . ESI(+)-MS in MeCN ( m / z assignment, % intensity): 366 ([CuPPh 3 + MeCN] + , 100), 587 ([Cu(PPh 3 ) 2 ] + , 42), 1140 ([M 2 + Cu] + , 40), 863 ([M + PPh 3 + Cu] + , 35).…”

“…Their corresponding EXAFS bond variance was 0.009(3) and 0.005(2) Å 2 for the Cu−N and Cu−P, respectively. These values were in very good agreement with those reported for complex [HB(pz) 3 ]Cu-(PPh 3 ) that contains the same [HB(pz) 3 ] − ligand (Cu−N = 2.076( 6)) 32 but lower than those observed in complex 10 (see Table 2). The elongation of the Cu−N bond distances in 10 is likely due to the electron withdrawing effect provided by the nitro groups in the chelate [HB(3-(NO 2 )pz) 3 ] − ligand.…”

In Vitroandin VivoAnticancer Activity of Copper(I) Complexes with Homoscorpionate Tridentate Tris(pyrazolyl)borate and Auxiliary Monodentate Phosphine Ligands

“…Characterization of this compound is in agreement with data already reported in the literature . ESI(+)-MS in MeCN ( m / z assignment, % intensity): 366 ([CuPPh 3 + MeCN] + , 100), 587 ([Cu(PPh 3 ) 2 ] + , 42), 1140 ([M 2 + Cu] + , 40), 863 ([M + PPh 3 + Cu] + , 35).…”

“…Their corresponding EXAFS bond variance was 0.009(3) and 0.005(2) Å 2 for the Cu−N and Cu−P, respectively. These values were in very good agreement with those reported for complex [HB(pz) 3 ]Cu-(PPh 3 ) that contains the same [HB(pz) 3 ] − ligand (Cu−N = 2.076( 6)) 32 but lower than those observed in complex 10 (see Table 2). The elongation of the Cu−N bond distances in 10 is likely due to the electron withdrawing effect provided by the nitro groups in the chelate [HB(3-(NO 2 )pz) 3 ] − ligand.…”

Syntheses and Spectroscopic and Structural Characterization of Silver(I) Complexes Containing Tertiary Phosphines and Hydrotris(pyrazol-1-yl)-, Hydrotris(4-bromopyrazol-1-yl)-, Hydrotris(3,5-dimethypyrazol-1-yl)-, and Hydrotris(3-methyl-2-thioxo-1-imidazolyl)borates

“…In the 1 H NMR spectra, as previously found in other poly(azol-1-yl)borate derivatives, − upfield resonances in the case of H(3), H(4), and CH 3 C(5) and downfield ones in the case of H(5) and CH 3 C(5) were detected. The shift is generally higher in derivatives of [HB(3,5-Me 2 Pz) 3 ] with respect to analogous derivatives of [HB(Pz) 3 ], and it is higher in derivatives containing P( o- tolyl) 3 , (PBz) 3 and P(2,4,6-Me 3 Ph) 3 .…”

“…The C−P−C angles (weighted average 104.0°) and the Ag−P−C (weighted average 114.45°) are comparable with the weighted value found in [HB(Pz) 3 ]Cu{PPh 3 }, whereas the mean N−Ag−N (bite angles) and N−Ag−P are smaller and greater, respectively, than those found in the analogous copper complex …”

“…The C-P-C angles (weighted average 104.0°) and the Ag-P-C (weighted average 114.45°) are comparable with the weighted value found in [HB(Pz) 3 ]Cu{PPh 3 }, 12 whereas the mean N-Ag-N (bite angles) and N-Ag-P are smaller and greater, respectively, than those found in the analogous copper complex. 12 Description of the Molecular Structure of [Hydrotris-(pyrazol-1-yl)borate]Ag[P(o-tolyl) 3 ] (2). The cell content consists of six discrete molecules.…”

In Vitroandin VivoAnticancer Activity of Copper(I) Complexes with Homoscorpionate Tridentate Tris(pyrazolyl)borate and Auxiliary Monodentate Phosphine Ligands

“…Characterization of this compound is in agreement with data already reported in the literature . ESI(+)-MS in MeCN ( m / z assignment, % intensity): 366 ([CuPPh 3 + MeCN] + , 100), 587 ([Cu(PPh 3 ) 2 ] + , 42), 1140 ([M 2 + Cu] + , 40), 863 ([M + PPh 3 + Cu] + , 35).…”

“…Their corresponding EXAFS bond variance was 0.009(3) and 0.005(2) Å 2 for the Cu−N and Cu−P, respectively. These values were in very good agreement with those reported for complex [HB(pz) 3 ]Cu-(PPh 3 ) that contains the same [HB(pz) 3 ] − ligand (Cu−N = 2.076( 6)) 32 but lower than those observed in complex 10 (see Table 2). The elongation of the Cu−N bond distances in 10 is likely due to the electron withdrawing effect provided by the nitro groups in the chelate [HB(3-(NO 2 )pz) 3 ] − ligand.…”

Syntheses and Spectroscopic and Structural Characterization of Silver(I) Complexes Containing Tertiary Phosphines and Hydrotris(pyrazol-1-yl)-, Hydrotris(4-bromopyrazol-1-yl)-, Hydrotris(3,5-dimethypyrazol-1-yl)-, and Hydrotris(3-methyl-2-thioxo-1-imidazolyl)borates

“…In the 1 H NMR spectra, as previously found in other poly(azol-1-yl)borate derivatives, − upfield resonances in the case of H(3), H(4), and CH 3 C(5) and downfield ones in the case of H(5) and CH 3 C(5) were detected. The shift is generally higher in derivatives of [HB(3,5-Me 2 Pz) 3 ] with respect to analogous derivatives of [HB(Pz) 3 ], and it is higher in derivatives containing P( o- tolyl) 3 , (PBz) 3 and P(2,4,6-Me 3 Ph) 3 .…”

“…The C−P−C angles (weighted average 104.0°) and the Ag−P−C (weighted average 114.45°) are comparable with the weighted value found in [HB(Pz) 3 ]Cu{PPh 3 }, whereas the mean N−Ag−N (bite angles) and N−Ag−P are smaller and greater, respectively, than those found in the analogous copper complex …”

“…The C-P-C angles (weighted average 104.0°) and the Ag-P-C (weighted average 114.45°) are comparable with the weighted value found in [HB(Pz) 3 ]Cu{PPh 3 }, 12 whereas the mean N-Ag-N (bite angles) and N-Ag-P are smaller and greater, respectively, than those found in the analogous copper complex. 12 Description of the Molecular Structure of [Hydrotris-(pyrazol-1-yl)borate]Ag[P(o-tolyl) 3 ] (2). The cell content consists of six discrete molecules.…”

In Vitroandin VivoAnticancer Activity of Copper(I) Complexes with Homoscorpionate Tridentate Tris(pyrazolyl)borate and Auxiliary Monodentate Phosphine Ligands

“…Characterization of this compound is in agreement with data already reported in the literature . ESI(+)-MS in MeCN ( m / z assignment, % intensity): 366 ([CuPPh 3 + MeCN] + , 100), 587 ([Cu(PPh 3 ) 2 ] + , 42), 1140 ([M 2 + Cu] + , 40), 863 ([M + PPh 3 + Cu] + , 35).…”

“…Their corresponding EXAFS bond variance was 0.009(3) and 0.005(2) Å 2 for the Cu−N and Cu−P, respectively. These values were in very good agreement with those reported for complex [HB(pz) 3 ]Cu-(PPh 3 ) that contains the same [HB(pz) 3 ] − ligand (Cu−N = 2.076( 6)) 32 but lower than those observed in complex 10 (see Table 2). The elongation of the Cu−N bond distances in 10 is likely due to the electron withdrawing effect provided by the nitro groups in the chelate [HB(3-(NO 2 )pz) 3 ] − ligand.…”

Syntheses and Spectroscopic and Structural Characterization of Silver(I) Complexes Containing Tertiary Phosphines and Hydrotris(pyrazol-1-yl)-, Hydrotris(4-bromopyrazol-1-yl)-, Hydrotris(3,5-dimethypyrazol-1-yl)-, and Hydrotris(3-methyl-2-thioxo-1-imidazolyl)borates

“…In the 1 H NMR spectra, as previously found in other poly(azol-1-yl)borate derivatives, − upfield resonances in the case of H(3), H(4), and CH 3 C(5) and downfield ones in the case of H(5) and CH 3 C(5) were detected. The shift is generally higher in derivatives of [HB(3,5-Me 2 Pz) 3 ] with respect to analogous derivatives of [HB(Pz) 3 ], and it is higher in derivatives containing P( o- tolyl) 3 , (PBz) 3 and P(2,4,6-Me 3 Ph) 3 .…”

“…The C−P−C angles (weighted average 104.0°) and the Ag−P−C (weighted average 114.45°) are comparable with the weighted value found in [HB(Pz) 3 ]Cu{PPh 3 }, whereas the mean N−Ag−N (bite angles) and N−Ag−P are smaller and greater, respectively, than those found in the analogous copper complex …”

“…The C-P-C angles (weighted average 104.0°) and the Ag-P-C (weighted average 114.45°) are comparable with the weighted value found in [HB(Pz) 3 ]Cu{PPh 3 }, 12 whereas the mean N-Ag-N (bite angles) and N-Ag-P are smaller and greater, respectively, than those found in the analogous copper complex. 12 Description of the Molecular Structure of [Hydrotris-(pyrazol-1-yl)borate]Ag[P(o-tolyl) 3 ] (2). The cell content consists of six discrete molecules.…”