Eur. J. Chem. volume 2, issue 4, P539-543 2011 DOI: 10.5155/eurjchem.2.4.539-543.55
Emtithal Ahmed El-Sawi, Tahia Bayoumy Mostafa, Hyam Ali Radwan
Abstract:

KEYWORDSIsatin-3-imine derivatives (1a-d) have been synthesized. These compounds were then converted into phosphorylated products 2a, 2c with triethylphosphite and 3a-d with triphenylphosphine. The structures of the new compounds were confirmed by elemental analyses, IR, UV/VIS, 1 H NMR, 13 C NMR and MS studies. The structure of compound 1a was also confirmed by single crystal X-ray diffraction studies. Compounds 1b-d and 3c-d exhibited potent antibacterial activity against Bacillus subtilis and Escherichia Coli. Compound 3a was found to exhibit antifungal activity against the tested organisms.Mass spectroscopy Phosphorylation Triphenylphosphine Schiff bases X-ray crystallography Antimicrobial activity

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