Abstract:A series of eleven compounds were synthesized from 6-methyl-N -(4-(pyridine-3-yl)pyrimidin-2-yl)benzene-1,3-diamine with various substituted carboxylic acid under solvent-free conditions using 1,1 -carbonyldiimidazole (CDI) as a catalyst. The yields of compounds are more than 72%. All the compounds were characterized by physical, spectroscopic, and elemental analysis. Compound 8b exhibited good inhibition towards antimicrobial activity compared to the other compounds.
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