2017
DOI: 10.5155/eurjchem.8.2.144-148.1551 View full text |Buy / Rent full text
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Abstract: A series of new fluoroquinolones analogs (3a-i) were prepared under conventional and microwave irradiation technique. Ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4dihydroquinoline-3-carboxylate (1) on reaction with boric acid and acetic anhydride in the presence of catalytic amount of zinc chloride under reflux, resulted in an unstable borate complex. Which was instantaneously treated with morpholine, piperidine, thiomorpholine, 2,6-dimethylmorpholine, 4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochlori… Show more

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