Synthesis and Antibacterial Activities of Antibacterial Peptides with a Spiropyran Fluorescence Probe

Chen, Lei; Zhu, Yu; Yang, Danling; Zou, Rongfeng; Wu, Junchen; Tian, He

doi:10.1038/srep06860

Cited by 14 publications

(15 citation statements)

References 49 publications

(56 reference statements)

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“…In general, Gram-positive bacteria have a simpler cell wall than Gram-negative bacteria, and the primary constituent is peptidoglycan, a polysaccharide. In contrast, Gram-negative bacteria have an additional outer bilayer membrane composed of lipopolysaccharides and phospholipids [ 27 , 28 ].…”

Section: Resultsmentioning

confidence: 99%

Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies

Savithri

Revanasiddappa

2018

Bioinorganic Chemistry and Applications

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Two novel oxidovanadium(IV) complexes with a new bidentate (O- and N-) imine-based ligand 2-((E)-(6-fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol (HL) were synthesized under in situ experimental condition where VOSO4 acts as a kinetic template in the ratio 2 : 1 (L : M) and mixed ligand complex using 1,10-phenanthroline (phen) in 1 : 1 : 1 (L : M : phen) ratio. The synthesized compounds were structurally characterized by microanalysis, magnetic susceptibility, FTIR, electronic spectra, TG/DTA, ESR, and molar conductance studies. Based on the spectral studies, the complexes have the general composition [VO(L)2] (C1) and [VO(L)phen] (C2) in a square pyramid geometrical fashion. The synthesized compounds were primarily screened for their in vitro growth inhibiting activity against different strains of bacteria, namely, E. coli, B. subtilis, S. aureus, and P. aeruginosa by the disc diffusion method. Also, the antifungal activity was determined against C. albicans and A. niger by the Bateman poisoned technique. The in vitro antioxidant activity of all the compounds was determined by DPPH free radical-scavenging assay. Intercalative mode of DNA-binding properties of the oxidovanadium(IV) complexes with calf-thymus DNA (CT-DNA) was investigated using UV, fluorescence spectra, and viscosity measurements.

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Section: Resultsmentioning

confidence: 99%

Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies

Savithri

Revanasiddappa

2018

Bioinorganic Chemistry and Applications

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“…The antimicrobial activity of the greenly synthesized silver nanoparticle was studied on two bacterial strain i.e., Gram negative ( E. coli (MTCC‐443)) and Gram positive ( S. aureus (MTCC‐3381)). The IC 50 values (the minimum concentration that produced 50% inhibition of bacterial growth) for greenly synthesized silver nanoparticle was calculated against a standard drug ( Ampicillin ) of concentration 10–80 μg/ml using nutrient broth.…”

Section: Characterization Of Greenly Synthesized Silver Nanoparticle mentioning

confidence: 99%

Green synthesis and characterization of silver nanoparticles by Allium cepa L. to produce silver nano‐coated fabric and their antimicrobial evaluation

Sharma

Pant

Rai

et al. 2017

Applied Organom Chemis

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This research work was proposed to study the antimicrobial activity of the silver nanocoated fabric with the purpose of producing good dressing and clothing material. We synthesized simple, ecofriendly, cost‐effective and sustainable silver nanoparticles by using the aqueous extract of Allium cepa L. Here, A. cepa L. acts as a good reducing and capping agent that produced stable silver nanoparticles having particle size of range 36 ± 1 to 98 ± 2 nm, Poly dispersiblity index 0.234 ± 0.61 to 1.023 ± 0.33 and Zeta potential ‐12 ± 1.5 mV to ‐26 ± 1.2 mV. The effect of temperature and extract volume used was considered for optimization of synthetic procedure. The nanocoated fabric was characterized for morphological study, size (using transmission electron microscopy (TEM) and field emission scanning electron microscopy (FE‐SEM) and zeta‐potential (Zeta Potentiometer). The presence of functional groups were observed by using attenuated total reflection‐Fourier transform infrared (ATR‐FTIR) and Raman spectroscopy. The crystallinity and structural property of the synthesized silver nanoparticles were studied in terms of Powder X‐ray diffraction (PXRD). An IC50 value and zone of inhibition was studied which demonstrate that the silver nanocoated fabric have an excellent antibacterial property against Gram‐negative (Escherichia coli) and Gram‐positive (Staphylococcus aureus) bacteria. Further nanocoated fabric material was washed (with function of time 0, 10, 25, and 50 laundry cycles) and still retained their anti‐bacterial activity towards both strain. Initially there was 52 μg/ml of silver nanoparticles on the cotton fabric but after 50 laundry cycle in 500 ml of distilled water the fabric showed 92% efficiency against gram positive and 90% efficacy toward gram negative bacteria. It was found that 4.16 μg/ml nano particles leached in case of S. Aureus and 5.2 μg/mL silver nanoparticles leached in case of E. coli. Nanocoated fabric material synthesized using green synthesis was found to be economical with good resistance to washing.

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“…[64][65][66][67][68][69][70][71][72] Searching for more rapid, economic, convenient and sensitive sensors has always been the focus of biomolecules recognition, which is of importance either in vitro or in vivo. [64][65][66][67][68][69][70][71][72] Searching for more rapid, economic, convenient and sensitive sensors has always been the focus of biomolecules recognition, which is of importance either in vitro or in vivo.…”

Section: Photochromic Sensors For Biomoleculesmentioning

confidence: 99%

Photochromic sensors: a versatile approach for recognition and discrimination

et al. 2015

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Photochromic sensors are widely used in detecting and monitoring analytes. Due to the photoswitchable properties, photochromic sensors show advantages in providing more recognition states and sensing information, and thus better sensitivity to external stimulations. Via reasonable design of photochromic sensors with various ionophores, dyes, platforms and metallic complexations, it is promising to achieve visual, sensitive and high-throughput detection. In this review, we summarized the applications of photochromic sensors in the areas of specific recognition and multi-analyte discrimination, based on their isomerization to light, as well as pH, temperature, solvent, etc. Specially, the multi-analyte determination was introduced, which has aroused extensive interest in recent years.

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Synthesis and Antibacterial Activities of Antibacterial Peptides with a Spiropyran Fluorescence Probe

Cited by 14 publications

References 49 publications

Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies

Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies

Green synthesis and characterization of silver nanoparticles by Allium cepa L. to produce silver nano‐coated fabric and their antimicrobial evaluation

Photochromic sensors: a versatile approach for recognition and discrimination

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