Synergistic effect of chemical crosslinking and addition of graphene-oxide in Chitosan—Hydrogels, films, and drug delivery

Marapureddy, Sai Geetha; Thareja, Prachi

doi:10.1016/j.mtcomm.2022.103430

Cited by 11 publications

(6 citation statements)

References 40 publications

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“…Finally, GA was added in the resultant suspensions. The physico-chemical characterizations demonstrated enhanced mechanical properties and increased stiffness in the CS/GO hydrogels [55]. Other disadvantages of chemical crosslinking methods are that these are considered to produce non-homogeneous hydrogels that have poor absorption properties.…”

Section: Chemical Crosslinking Approachmentioning

confidence: 99%

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Novel Photothermal Graphene-Based Hydrogels in Biomedical Applications

Croitoru,

Ficai,

Ficai

2024

Polymers

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In the last decade, photothermal therapy (PTT) has attracted tremendous attention because it is non-invasive, shows high efficiency and antibacterial activity, and minimizes drug side effects. Previous studies demonstrated that PTT can effectively inhibit the growth of bacteria and promotes cell proliferation, accelerating wound healing and tissue regeneration. Among different NIR-responsive biomaterials, graphene-based hydrogels with photothermal properties are considered as the best candidates for biomedical applications, due to their excellent properties. This review summarizes the current advances in the development of innovative graphene-based hydrogels for PTT-based biomedical applications. Also, the information about photothermal properties and the potential applications of graphene-based hydrogels in biomedical therapies are provided. These findings provide a great potential for supporting their applications in photothermal biomedicine.

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Section: Chemical Crosslinking Approachmentioning

confidence: 99%

Section: Fabrication Of Graphene-based Hydrogelsmentioning

confidence: 99%

Novel Photothermal Graphene-Based Hydrogels in Biomedical Applications

Croitoru,

Ficai,

Ficai

2024

Polymers

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“…By incorporating divalent or trivalent ions, such as calcium or zinc ions, into the chitosan solution, gelation occurs through the ionic interactions between chitosan chains and the ions. 148,152 regarded tripolyphosphate and 153 glutaraldehyde as the best crosslinkers, which impart high mechanical strength and structural integrity. Their combination could reveal better results but showed poor cell viability.…”

Section: Ionic Gelationmentioning

confidence: 99%

“…201 Additionally, selfhealing hydrogels can be combined with other technologies, such as nanoparticles 232,233 or microneedles, 234,235 to further enhance drug delivery capabilities. 153 Marapureddy et al 2022 induced nanosheets of graphene oxide to improve the mechanical strength and to obtain a pH-responsive sustained drug release. In addition to hydrogels 153 could fabricate chitosan films using the same.…”

Section: Drug Deliverymentioning

confidence: 99%

Self-healing, injectable chitosan-based hydrogels: structure, properties and biological applications

J.,

Solanki,

Dhanka

et al. 2024

Mater. Adv.

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“…Chitosan is a natural polymer that emerged as one of the useful nanocarriers for various therapeutic agents in transdermal drug delivery. Functional properties such as biocompatibility and biodegradability [ 148 ] have facilitated the development of chitosan-based nanocarriers for medicinal applications [ 149 , 150 ]. Slow polymer erosion in chitosan allows effective drug encapsulation [ 151 ] for sustained and controlled drug release with low toxicity.…”

Section: Chitosan Npsmentioning

confidence: 99%

Recent Development of Nanomaterials for Transdermal Drug Delivery

et al. 2023

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Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient convenience, avoids first-pass hepatic metabolism, provides local targeting, and reduces effective drug toxicities. Nanomaterials provide alternatives to conventional transdermal drug delivery including patches, gels, sprays, and lotions, but it is crucial to understand the transport mechanisms involved. This article reviews the recent research trends in transdermal drug delivery and emphasizes the mechanisms and nano-formulations currently in vogue.

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Synergistic effect of chemical crosslinking and addition of graphene-oxide in Chitosan—Hydrogels, films, and drug delivery

Cited by 11 publications

References 40 publications

Novel Photothermal Graphene-Based Hydrogels in Biomedical Applications

Novel Photothermal Graphene-Based Hydrogels in Biomedical Applications

Self-healing, injectable chitosan-based hydrogels: structure, properties and biological applications

Recent Development of Nanomaterials for Transdermal Drug Delivery

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