Symptomatic treatment of acute tonsillo-pharyngitis patients with a combination of Nigella sativa and Phyllanthus niruri extract

The use of Phyllanthus niruri L. as an immunomodulator for the treatment of infectious diseases in clinical settings

“…The reductions in Phyllanthus-Nigella treated group (29.29 ± 19.46 or 58.71% from baseline; and 33.81 ± 18.56 or 62.06% from baseline, respectively) were greater (P = 0.008 and P = 0.001, respectively) than that of the placebo (22.72 ± 19.08 or 46.44% from baseline, and 26.40 ± 20.36, or 48.10% from baseline, respectively). Treatment with Phyllanthus-Nigella extract also provided a complete relief of the sore-throat in a significantly greater proportion of patients than the placebo did (60.0% versus 38.4%, P = 0.022) [79]. In the study, Phyllanthus-Nigella extract was efficacious in relieving the symptoms of acute tonsillopharyngitis with any baseline severity ranging from mild to severe.…”

“…In a randomized, placebo-controlled study, P. niruri extract was given in a combined preparation with Nigella sativa (N. sativa) extract, which is known to possess an anti-inflammatory property [79,80]. One hundred and ninety-six enrolled patients were randomly allocated to receive either the active capsules containing a combination of P. niruri 50 mg extract and N. sativa 360 mg extract, or the matching placebo, under a double-blind fashion.…”

Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver

“…Similarly, black seed oil was shown to be an effective adjuvant for the treatment of patients with allergic diseases [21] . In another clinical study, significant benefits of Nigella sativa extract in the treatment of acute tonsillopharyngitis was shown [22] . Also, it was shown that Nigella sativa has antiepileptic effects in children with refractory seizures [23] .…”

Antidiabetic Properties of a Spice Plant Nigella sativa

“…Smooth muscle relaxant, anticholinergic and antihistaminic effects of N. sativa have been found useful in patients of asthma in another clinical trial [68]. Due to its antihistaminic, antiinflamatory, antioxidant and antibacterial effects, N. sativa was found to be useful in patients of acute tonsillo-pharyngitis in a randomized double blind placebo controlled clinical trial [69]. In traditional medicine, N. sativa has been known for its anticonvulsant effects.…”