Symmetric Erythema of the Soles

Ultrasonography detects symmetrical lividities of the soles of the feet: a non‐hyperhidrosis case treated with AlCl3 solution

“…As the histopathological characteristics of SyL, Hitch et al. reported: (i) parakeratosis and hypergranulosis; (ii) edema and vascular dilation; and (iii) moderate cellular infiltration 3 . We did not perform a skin biopsy; however, our ultrasonography observations were consistent with the pathological characteristics of SyL.…”

“…This case of SyL without hyperhidrosis responded to AlCl 3 solution. Our survey of cases found only a few reports in English of SyL; 1–5 however, a number of cases have been reported in Japan. Thus, we reviewed the well‐documented Japanese reports to obtain clues for treatment 6–23 .…”

“…We summarize the clinical information of the 39 SyL cases in Table 1. As Hitch and Hansen described, SyL tends to be accompanied by hyperhidrosis 3 . In fact, of the 39 Japanese cases, 24 (62%) were so accompanied.…”

“…Symmetrical lividities of the soles of the feet (SyL) is an inflammatory skin disease with symptoms that include well‐defined, blue‐red, edematous eruptions on the soles 1,2 . Based on the evidence that SyL is accompanied by hyperhidrosis and is associated with confining footwear, SyL is thought to be caused by several factors, including humid environment, trauma, and pressure 3,4 . Concerning treatments, several reports have shown the effectiveness of feet‐resting, topical steroid ointment, urea cream, and aluminum chloride (AlCl 3 ) solution; however, a definitive treatment has not been clearly identified 5 .…”

Symmetrical Lividity of the Palms and Soles

“…mild perivascular infiltration of lymphocytes and occasional polymorphonuclear leukocytes, and di lated, engorged blood vessels especially in the superficial plexus. 3 Nelson noted only a few pyknotic nuclei in the stratum corneum which was greatly thickened and individual cells were swollen. 6 Again, hypergranulosis and acanthosis, dermal edema, vascular dilation, and a scattered round cell infiltrate were present.…”