Suspected Cat-to-Human Transmission of SARS-CoV-2, Thailand, July–September 2021

Sila, Thanit; Sunghan, Jutapoln; Laochareonsuk, Wison; Surasombatpattana, Smonrapat; Kongkamol, Chanon; Ingviya, Thammasin; Siripaitoon, Pisud; Kositpantawong, Narongdet; Kanchanasuwan, Siripen; Hortiwakul, Thanaporn; Charernmak, Boonsri; Nwabor, Ozioma Forstinus; Silpapojakul, Khachornsakdi; Chusri, Sarunyou

doi:10.3201/eid2807.212605

Cited by 121 publications

(144 citation statements)

References 11 publications

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“… 8 Similarly, the suspected cat-to-human transmission of SARS-CoV-2 in Thailand was also reported, where SARS-CoV-2 from the owner infected the cat, and was then transmitted to the veterinarian. 9 Besides, many Omicron mutations, such as Q493R, Q498R and N501Y mutations in S protein, have been reported in adapted strains of mice, leading to the enhancement of viral adaptation and receptor engagement in mouse host, especially in aged mice, 10 , 11 which could have served as an incubator of SARS-CoV-2 variants. 12 Interestingly, both Omicron BA.1 and BA.2 S-trimers could bind with high affinity to mouse ACE2, while the ancestral SARS-CoV-2 S-trimer bound well to cat ACE2, rather than mouse ACE2, suggesting a possible human-cat-mouse-human evolution pathway for Omicron BA.1 and BA.2 sublineages.…”

Section: Origin Of the Omicron Variantmentioning

confidence: 99%

Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages

Xia

Wang

Zhu

et al. 2022

Sig Transduct Target Ther

120

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Recently, a large number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continuously emerged and posed a major threat to global public health. Among them, particularly, Omicron variant (B.1.1.529), first identified in November 2021, carried numerous mutations in its spike protein (S), and then quickly spread around the world. Currently, Omicron variant has expanded into more than one hundred sublineages, such as BA.1, BA.2, BA.2.12.1, BA.4 and BA.5, which have already become the globally dominant variants. Different from other variants of concern (VOCs) of SARS-CoV-2, the Omicron variant and its sublineages exhibit increased transmissibility and immune escape from neutralizing antibodies generated through previous infection or vaccination, and have caused numerous re-infections and breakthrough infections. In this prospective, we have focused on the origin, virological features, immune evasion and intervention of Omicron sublineages, which will benefit the development of next-generation vaccines and therapeutics, including pan-sarbecovirus and universal anti-CoV therapeutics, to combat currently circulating and future emerging Omicron sublineages as well as other SARS-CoV-2 variants.

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Section: Origin Of the Omicron Variantmentioning

confidence: 99%

Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages

Xia

Wang

Zhu

et al. 2022

Sig Transduct Target Ther

120

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“…After the COVID-19 pandemic, anxiety levels increased due to pervasive uncertainty and fear of disease [ 24 , 25 ]. Despite reports that SARS-CoV-2 can be spread by dogs, concerns of contracting COVID-19 from a dog was low, with 88% of participants reporting “little” to “no concern” ( Figure 4 A, Table S4 ) [ 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Though most patients had little to no concern of contracting COVID-19 from dogs and the risk of zoonotic transmission is considered low, it is important for handlers and facilities with therapy animals to adhere to proper health protocols and the use of personal protective equipment, to minimize the risk of spread and ensure safety for both the canine and patients [ 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ].…”

Section: Resultsmentioning

confidence: 99%

Patient and Caregiver Perceptions of Animal Assisted Activity in Orthodontics

Cass

Bocklage

Sulkowski

et al. 2022

Animals

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Dental anxiety affects up to 21% of children and 80% of adults and is associated with lifelong dental avoidance. Animal assisted activity (AAA) is widely used to reduce anxiety and pain in medical settings and has promise in dentistry. The primary objective of this study was to evaluate caregiver and patient perceptions of canine AAA in orthodontics. A cross-sectional survey consisting of pre-tested and validated questions was conducted (n = 800) including orthodontic patients (n = 352 minors, n = 204 adults) and parents/caregivers (n = 244) attending university orthodontic clinics. In this study, AAA and dog therapy were not used or tested for dental anxiety management. More than a third of orthodontic patients (37%) had moderate or greater anxiety related to care. Participants believed that therapy animals would make dental experiences more enjoyable (75%) and reduce anxiety (82%). There was little to no concern expressed regarding cleanliness (83%), allergies (81%), and safety (89%) with a therapy animal in dental settings. Almost half of the participants would preferentially select an orthodontic office offering AAA. In light of the COVID-19 pandemic, we assessed whether perceptions of AAA changed before and after the shutdown of dental offices, with no significant differences. Across patients and caregivers, the responses support the use of AAA in orthodontic settings with minimal concerns.

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“…Furthermore, the genomic sequences characterising the SARS-CoV-2 isolates obtained from the cat, as well as from its owners and from the vet, were shown to overlap with each other. 1 However, it should also be noted that while there is significant biological plausibility that the virus entered the vet's body through the ocular route -since she wore an N95 protective mask during the clinical examination of the cat -her anti-SARS-CoV-2 immunisation status was not reported.…”

Section: Zoonotic Diseasementioning

confidence: 99%

Transmission of SARS‐CoV‐2 from a cat to a person

Guardo

2022

Veterinary Record

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Suspected Cat-to-Human Transmission of SARS-CoV-2, Thailand, July–September 2021

Abstract: A veterinarian in Thailand was diagnosed with COVID-19 after being sneezed on by an infected cat owned by an infected patient. Genetic study supported the hypothesis of SARS-CoV-2 transmission from the owner to the cat, and then from the cat to the veterinarian.

Cited by 121 publications

References 11 publications

Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages

Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages

Patient and Caregiver Perceptions of Animal Assisted Activity in Orthodontics

Transmission of SARS‐CoV‐2 from a cat to a person

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