Survey of oral chemotherapy safety and adherence practices of hospitals in Spain

Conde-Estévez, David; Salas, E.; Albanell, Joan

doi:10.1007/s11096-013-9858-9

Cited by 15 publications

(11 citation statements)

References 27 publications

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“…Regardless of many demographic considerations, including gender, socioeconomic status and education level, the patients' difficulty in adhering to oral oncological agents has been well documented across tumor types, including solid tumors (gastrointestinal stromal tumors) [46], male breast cancer [47,48], pancreatic neuroendocrine tumors [49], non-small cell lung cancer [50] and renal cell cancer [51], in countries all across the world [52,53,54]. This has also been documented in hematological malignancies [2] including the whole age spectrum of CML patients: both younger [5] and older age groups [55].…”

Section: Adherence To Oral Tki Therapymentioning

confidence: 99%

Chronic Myeloid Leukemia in Adolescents and Young Adults: Patient Characteristics, Outcomes and Review of the Literature

Pemmaraju

Cortés

2014

Acta Haematol

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Over the past two decades, many improvements have been made in the management of patients with leukemia. Research in this field most often focuses on the youngest and oldest patient age groups. However, the population of patients in between those age groups has received relatively little attention with few studies specifically focusing on them. This important ‘age gap' has demonstrated a unique, difficult-to-treat group of patients known as adolescents and young adults, or AYAs. Variably defined in the literature as patients from late teenage years to the age of up to 40 years, the AYA group of patients represents a vulnerable subset of patients now identified to require its own focus, development of therapeutic strategies and parallel emphasis on special support systems involving multidisciplinary psychosocial care. Despite the great advancements that have been realized for patients with chronic myeloid leukemia (CML), the AYA group has seldom been the focus of specific reports and studies, and the outcome appears to lag behind the general population. This review focuses on this subset of AYA patients with CML and summarizes the available data and recent developments, challenges and treatment options for this group of patients.

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Section: Adherence To Oral Tki Therapymentioning

confidence: 99%

Chronic Myeloid Leukemia in Adolescents and Young Adults: Patient Characteristics, Outcomes and Review of the Literature

Pemmaraju

Cortés

2014

Acta Haematol

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“…[5,10,13] The prescriptions in RICK hospital are hand written and it was attached with patient file when coming at the pharmacy for dispensing. May studies [3,4,17] reported that the using of the hand written prescription was commonly prevalent, while the using of electronic system prescription was highly encouraged and stated in many guidelines [11,12] which may reduce errors.…”

Section: Discussionmentioning

confidence: 99%

“…While in Bourmaud et al [3] study 28% of the centers had developed addition of therapeutics education materials for the patient at the first visit, while 12% of the clinicians who participated in this study holding regular workshops with their patients. In Conde-Estévez et al [4] 44.2% of hospitals classified as level II and performed an initial counseling visit with a pharmacist by 98.8%. It also providing written educational materials and monitoring adherence.…”

Section: Discussionmentioning

confidence: 99%

“…[1,2] With approving of new targeted molecular therapies, more than 25% antineoplastic agents currently being developed are oral drugs. [3,4] These shifting oncologists to prescribe oral chemotherapy, as it has many social and economic advantages for patients including increased control and convenience for the patient, potential increase in the quality of life, sustained medication exposure and potential reduction in travel costs and use of health care resources. [1] While there are several advantages to prescribing oral chemotherapy, one must bear in mind that home-based chemotherapy may continue for some time without professional supervision.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Pharmacist Dispensing Practices and their Educational Role Toward Patients on Oral Cytotoxic Drugs Regimen in Radiation and Isotopes Center at Khartoum, Sudan

Mohamed¹,

Mousnad²

2020

JPPCM

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Background: Increasing use of oral cytotoxic chemotherapy among cancer patient in Sudan, rising important concern about safety practicing and using of these drugs. This study aimed to assess and demonstrate pharmacist dispensing pattern and their educational role toward patients on oral cytotoxic drugs regimen in Radiation and Isotopes Center at Khartoum (RICK). Methods: Across-sectional study was carried out at (RICK) hospital pharmacies. Data collected by using self-administered questionnaire distributed to all staff in active works (40 pharmacists) during February 2016. Results: All the participants responded to the questionnaire. The study reported variation among pharmacists when checking prescription. In which 97.4% of them checked drug name while only 76.9% calculating the dose according to the body surface area. For the patients-pharmacist counseling and it is effectiveness the study revealed that 77.5% of pharmacist providing counseling for the patient at the first visit. 75% of pharmacists counseling the drugs regimen. 28.1% of them including the drugs side effects and management. The counseling of the drugs handling and storage was registered by 65.6% of the participants. 53.1% of the pharmacists advice the patients to swallow the tablets and not crush it. The drugs interaction was counseled by 9.4% and only 2% of pharmacists counseled patients about medications teratogenicity. The finding revealed significant association between pharmacist experience and counseling practice by chi-square (p-value=0.008) while, the hospital training and staff attending has on significant association with (p-value=0.922, p-value=0.479). Conclusion: The study concluded that dispensing practice among pharmacists was main divers. Moreover, most of the pharmacists followed no standard when counseling patients and their experience becomes the main source when educating them.

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“…9,10 Earlier studies have reported data for a single site or disease type 8 or used surveys as surrogates of practice achievement 9,[17][18][19] or patient and caregiver practices. 20,21 In contrast, we present multi-institutional chart abstraction data for patients with a variety of malignancies.…”

Section: Discussionmentioning

confidence: 99%

Administration of Oral Chemotherapy: Results From Three Rounds of the Quality Oncology Practice Initiative

Zerillo

Pham

Kadlubek

et al. 2015

JOP

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Survey of oral chemotherapy safety and adherence practices of hospitals in Spain

Cited by 15 publications

References 27 publications

Chronic Myeloid Leukemia in Adolescents and Young Adults: Patient Characteristics, Outcomes and Review of the Literature

Chronic Myeloid Leukemia in Adolescents and Young Adults: Patient Characteristics, Outcomes and Review of the Literature

Assessment of Pharmacist Dispensing Practices and their Educational Role Toward Patients on Oral Cytotoxic Drugs Regimen in Radiation and Isotopes Center at Khartoum, Sudan

Administration of Oral Chemotherapy: Results From Three Rounds of the Quality Oncology Practice Initiative

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