Surgical treatment for postgastrectomy syndromes: Actual problems

Chernousov, Alexandr F.; Хоробрых, Т В; Zubareva, M.; Gorbunov, A.A.; Abdulkhakimov, N M; Uddin, L. N.; Khorobrykh, V.; Gelmutdinova, E R

doi:10.29296/25877305-2019-06-01

Cited by 4 publications

(3 citation statements)

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“…ПС характеризуются многообразием симптоматики, отражающей нарушения функций различных органов и систем организма больных, перенесших резекцию желудка. Пептическая язва гастроэнтероанастомоза (ПЯГ) среди пациентов с ПС наблюдается в 11,8-15% случаев [5].…”

Section: Introductionunclassified

“…Частой причиной рецидивирующей ПЯГ является сохранение интенсивного кислотообразования вследствие активации вагуса и нарушения парасимпатической регуляции. Помимо этого, в патогенезе ПЯГ имеет значение повреждение сосудов и нервов при формировании анастомоза, спазм кишечной мускулатуры, нарушение микроциркуляции, трофические изменения слизистой, агрессивное воздействие желудочного сока, декомпенсация защитных факторов слизистой оболочки [5,6,8,9].…”

Section: Introductionunclassified

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The vegetative disbalance and its eﬀect on the formation of peptic ulcer of gastroenteroanastomosis

Antonyan

Левитан

Zurnadghyants

et al. 2022

jour

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Research objective. To study the eﬀect of vegetative nervous system dysfunction on mechanisms of peptic ulcer of gastroenteroanastomosis formation and to improve the results of treatment of patients after gastric resection for peptic ulcer disease.Material and methods. The study included 30 patients with peptic ulcers of gastroenteroanastomosis being operated on for gastric ulcer and duodenal ulcer. Instrumental research included: cardiorhythmography, esophagogastroduodenoscopy, intragastric pH-metry, electrogastrography, laser Doppler ﬂ owmetry.Results. In patients with peptic ulcers of gastroenteroanastomosis, according cardiorhythmography, parasympathicotonia prevailed in 20 (66,7%) patients, sympathicotonia was observed in 8 (26,7%) patients, eutonia — in 2 (6,6%) patients. Microcirculation data against the background of sympathicotonia were signiﬁ cantly lower than in the control group (p<0,05) and lower than those in parasympathicotonia and eutonia. With the hyperkinetic type of motility, the predominance of parasympathicotonia(87,5% patients), while the acid-producing function of the stomach was increased in 70% patients (рН 0,9±0,3). Autonomic dysfunction and helicobacteriosis were observed in 26 patients (86,6%). Correlation analysis between cardiorhythmography data and gastric acidity established positive correlation of average strength (r=0,726), which determined the important role of acid-peptic exposure against the background of an increase in the tone of the parasympatic part of the vegetative nervous system. With the predominance of parasympathicotonia, M-anticholinergic Нyoscine butylbromide was included in the complex therapy. After the treatment, the results of cardiorhythmography showed the normotensive nature of the cardiorhythmograms, motor data improved in 60% patients, the acidity data corresponded to the normality (рН 1,2–2,0).Conclusions. The results of the study showed the predominance of parasympathicotonia in patients with peptic ulcers of gastroenteroanastomosis, which contributes to impaired microcirculation, motor- evacuation and secretory functions of the gastric stump and creates conditions for persistence. The сardiorhythmography made it possible to objective assess of the state of the vegetative nervous system. The inclusion of hyoscinebutylbromide in complex treatment with the predominance of parasympathicotonia has a modulating eﬀect on the vegetative nervous system.

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Section: Introductionunclassified

The vegetative disbalance and its eﬀect on the formation of peptic ulcer of gastroenteroanastomosis

Antonyan

Левитан

Zurnadghyants

et al. 2022

jour

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“…Введение. Синдромы оперированного желудка после резекции по поводу язвенной болезни по данным разных авторов встречаются в 15-65 % [1][2][3][4][5][6]. Выявлены особенности развития постгастрорезекционных расстройств в зависимости от способа резекции желудка.…”

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Prophylaxis of Anastomositis After Stomach Resection

Antonyan,

Kuchin,

Kudba

et al. 2023

Astrakhan Medical Journal

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The clinical, immunological and endoscopic features of anastomositis were studied in patients after the stomach resection according to Billroth II in various modifications because of peptic ulcer disease. The study revealed the relationship in development of anastomositis with the level of populations T-lympho cytes, immunoregulatory index, circulating immune complexes, R-proteins in the early postoperative period as well as before the operation. Disturbances in the immune system may lead to decrease in stability of mucosa and to the increase of aggressive factors. The severity of disturbances in the functioning of the immune system is interrelated with the presence of Helicobacter pylori infection. The higher the antibody titers to the antigen CagA Helicobacter pylori, the more severe there may be the manifestations of immunopathological reactions and the more severe the clinical signs of anastomositis. Immunological indicators and their dynamics may be used both for the early diagnosis of anastomositis, and for the prognosis and prophylaxis of this postoperative complication.

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Результаты Проксимальной Резекции Желудка В Зависимости От Методов Реконструкции Желудочно-Кишечного Тракта

Тишакова¹,

Ручкин²,

Грицкевич³

et al. 2021

Естественные И Технические Науки

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Аннотация. В статье отражены результаты исследования, целью которых было оценить эффективность и доказать целесообразность применения изоперистальтической еюногастропластики (модификация операции Merendino-Dillard) в качестве способа первичной реконструкции после субтотальной проксимальной резекции желудка.

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Surgical treatment for postgastrectomy syndromes: Actual problems

Cited by 4 publications

References 0 publications

The vegetative disbalance and its eﬀect on the formation of peptic ulcer of gastroenteroanastomosis

The vegetative disbalance and its eﬀect on the formation of peptic ulcer of gastroenteroanastomosis

Prophylaxis of Anastomositis After Stomach Resection

Результаты Проксимальной Резекции Желудка В Зависимости От Методов Реконструкции Желудочно-Кишечного Тракта

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