2000
DOI: 10.1177/030089160008600101 View full text |Buy / Rent full text
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Abstract: Surgical resection remains a milestone in the treatment of colorectal metastases to the liver. There is a distinct subset of patients who benefit from surgical resection in terms of longer survival or definitive cure. The main effort of the surgical oncological regards the safety of the procedure and the adequacy of the recommendation. Many studies, some of them including multivariate analysis, have shown the presence of prognostic determinants of long-term survival and prognostic indexes of the outcome after … Show more

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“…We do not know whether these figures reflect true unresectability or just a strategy aiming to select the most favourable cases. However, current literature [2][3][4][5] supports the concept that liver resection for colorectal metastases should be done when the complete excision of all demonstrable tumours with clear resection margins, even of less than 1 cm, is feasible. The presence of other negative prognostic factors only suggests that the chance of failure is high, and surgical indication requires a careful evaluation of the risk-to-benefit ratio in each individual patient.…”
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“…We do not know whether these figures reflect true unresectability or just a strategy aiming to select the most favourable cases. However, current literature [2][3][4][5] supports the concept that liver resection for colorectal metastases should be done when the complete excision of all demonstrable tumours with clear resection margins, even of less than 1 cm, is feasible. The presence of other negative prognostic factors only suggests that the chance of failure is high, and surgical indication requires a careful evaluation of the risk-to-benefit ratio in each individual patient.…”
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“…Thus all the 151 patients had metastases confined to the liver and 136 of them (90%) had a performance status 0 or 1 [1]. The criteria of unresectability are usually multifactorial and have been well described in Bismuth's article [2]. These classical criteria include the number of metastases and/or their size and/or their location in both lobes and/or the percentage of liver involvement and/or the invasion ofintra-hepatic vascular structures.…”
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