Surgical outcomes of 43 cases with adenoid cystic carcinoma of the external auditory canal

Adenoid cystic carcinoma of the head and neck – An update

“…It is the most commonly reported malignant tumor of the minor salivary glands (MSGs) [1] and is also one of the most common cancers of the major salivary glands (the parotid, submandibular and sublingual salivary glands) [4]. AdCC can also involve lacrimal and ceruminous glands as well as other sites in the head and neck, including the nasal and paranasal sinuses, trachea and larynx [1,[6][7][8][9][10].…”

Correlation between the pathology and clinical presentations in patients with adenoid cystic carcinoma of the external auditory canal

“…Previous reports have indicated that ACC of the external auditory canal is a tumor of adulthood, with a definite peak incidence in the fourth and fifth decades of life, occurring rarely in children and adolescents . In our study, the median age at diagnosis was 49 years.…”

“…Adenoid cystic carcinoma (ACC) is a rare primary malignancy in the external auditory canal. It is noted for its indolent course, high rate of recurrence, and eventual death of the patient . An ACC of the external auditory canal, like ACC in general, is characterized by considerable histological diversity and 3 basic growth patterns: cribriform, tubular, and solid .…”

“…Given its locally aggressive behavior, the primary surgical procedures for an ACC of the external auditory canal should be more extensive with a parotidectomy recommended in addition to lateral temporal bone resection. A superficial parotidectomy has been shown to increase both the overall and disease‐free survival in an ACC of the external auditory canal . Although several authors have observed occult invasion of the parotid gland, and suggested parotidectomy as a mandatory procedure to secure adequate surgical margins even in the early stages of an ACC, the clinicopathological basis for this remains unclear.…”

Salivary Gland Cancers: A Survey through History, Classifications and Managements

“…On the other hand, it is the most common malignancy of minor salivary gland tumors with a proportion ranging from 32 to 71% [67]. AdCC may involve other sites and glands such as lacrimal and ceruminous glands as well as nasal and paranasal sinuses, larynx and trachea [32,67,[71][72][73][74]. AdCC is mostly found in the parotid, submandibular and minor salivary glands.…”