Cochrane Database of Systematic Reviews 2007
DOI: 10.1002/14651858.cd001350.pub4
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Surgical interventions for lumbar disc prolapse

Abstract: Surgical discectomy for carefully selected patients with sciatica due to lumbar disc prolapse provides faster relief from the acute attack than conservative management, although any positive or negative effects on the lifetime natural history of the underlying disc disease are still unclear. Microdiscectomy gives broadly comparable results to open discectomy. The evidence on other minimally invasive techniques remains unclear (with the exception of chemonucleolysis using chymopapain, which is no longer widely … Show more

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Cited by 204 publications

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“…In the context of previous related systematic reviews, our findings are in general agreement that surgery for disc herniation provides faster short-term relief over non-surgical management for sciatica throughout the first 3 months, [14,45,46] 6 months [47] and 1-year follow-up [10], although no differences were found after 1 and 2 years in one review [14]. Regarding spinal stenosis, our results are also in general agreement with several reviews, that surgery is superior to non-surgical therapy through 1 to 2 years [45].…”
Section: Discussion
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confidence: 87%