Surgarcane biopolymer patch in femoral artery angioplasty on dogs

Aguiar, José Lamartine de Andrade; Lins, Esdras Marques; Marques, Silvio Romero; Coelho, Antônio Roberto de Barros; Rossiter, Renata de Oliveira; Melo, Roberto José Vieira de

doi:10.1590/s0102-86502007000700015

Cited by 21 publications

(24 citation statements)

References 16 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This line of thinking is due to the results obtained in other papers in which this material was used in dense form, as cited by other authors, for the repair of defects in arterial vessels, membranes, the urinary bladder and hard material [11][12][13][14][15] .…”

Section: Resultsmentioning

confidence: 99%

“…Whatever the cause, the healing of these defects follows a sequence of events that can be divided into three phases, in accordance with the morphological changes: the inflammatory phase, a repair phase and a remodelling one [8][9][10][11][12][13][14][15][16] . In the inflammatory phase, hematomas are formed and reorganized, platelet growth factors are released and tissue formed which is rich in progenitory cells derived from within the bone tissue itself and peripheral blood.…”

Section: Introductionmentioning

confidence: 99%

Comparative study of the areas of osteochondral defects produced in the femoral condyles of rabbits treated with gel of sugarcane biopolymer

Albuquerque¹,

Aguiar²,

Santos³

et al. 2011

Acta Cir. Bras.

Self Cite

View full text Add to dashboard

PURPOSE: To measure the healed areas of osteochondral defects produced in femoral condyles of rabbits filled with biopolymer sugar cane gel and to compare these with those of the control group at 90, 120 and 180 days. METHODS: A study was made of 16 New Zealand rabbits, 6 and 7 months old, weighing between 2 and 2.5 kg. Defects of 3.2 x 4 mm were made, with trephine, in the femoral condyles of the right and left knees. As to the study group defects of the medial and lateral condyles of the right knee were used which were filled with Biopolymer Sugar Cane Gel; as to the Control Group defects of the medial and lateral condyles of the left t knees were used which were left open for natural healing. The defects were analyzed at 90, 120 and 180 days after surgery. After euthanasia, the knees were removed and fixed in Bouin's solution for later digital photographic documentation with a digital camera. The areas healed were measured in both the study and control groups using the images obtained from an Image-J® program. Statistical analysis was conducted using the non-parametric Mann-Whitney test. RESULTS: There were no significant differences between the means of the healed areas in the study and control groups at 90, 120 and 180 days after surgery. CONCLUSION: The dimension of the healed areas of the defects treated with the biopolymer sugar-cane gel in the study group was similar to those of the control group, which healed naturally.

show abstract

“…Aguiar et al 13 and Martins, et al 14 reported that among treatments with film of cellulosic polysaccharide there were no cases of infection and the tolerance to the material was satisfactory and there were no adverse reactions.…”

Section: Discussionmentioning

confidence: 99%

Spongy film of cellulosic polysaccharide as a dressing for aphthous stomatitis treatment in rabbits

Teixeira¹,

Pereira²,

Ferreira³

et al. 2014

Acta Cir. Bras.

Self Cite

View full text Add to dashboard

PURPOSE:To develop an experimental model of acute inflammation, like aphthous ulcers, in oral cavity of rabbits, and also, to evaluate the results of the application of a polysaccharide spongy film of molasses from sugar cane as assist treatment in the healing process. METHODS:Twenty adult rabbits weighting between 2.5 kg and 3.9 kg were divided into two groups: experimental and control infected ulcers were induced on the jugal mucosa by surgical excision. They were treated at the experimental group by curettage and dressing with spongy film of cellulosic polysaccharide film, whereas saline solution was used in the control group. Temporal evolution of the healing area, histopathology and bacteriological analysis were used to evaluate the healing process on the 3 rd (D3), 7 th (D7) and 11 th days (D11). RESULTS:The healing time and bacteriological study showed no statistical differences on the group means. Analyzing the histopathology of the experimental group we verified epithelial hyperplasia from D3 to D11, instead in the control group there was a greater clutter of the epithelial cells from the D3 to D11. CONCLUSION:The experimental model used caused aphthous ulcers and the polysaccharide sponge film can be used as an aid in the symptomatic treatment and healing of the ulcerative lesions of the oral mucosa.

show abstract

“…Desta forma, promover a adesão de células a um biomaterial pode ajudar na integraçaõ do tecido conectivo mole com o implante, repercutindo no desenvolvimento de novas ferramentas (CARVALHO et al, 2010;MAGER et al, 2011;PIRES et al, 2015). Os biopolímeros despontam como biomateriais inovadores, em função da sua biocompatibilidade e o biopolímero de cana-deaçúcar (BCA), um exopolissacarídeo produzido a partir da fermentação do melaço pela bactéria Zoogloea sp., vem sendo utilizado em diversas aplicações nas áreas das Ciências da Saúde e da Biologia (PATERSON-BEEDLE et al, 2000;CASTRO, et al, 2004;AGUIAR et al, 2007;CAVALCANTE, et al, 2007;SILVEIRA et al, 2007;MAYER et al, 2011;MARTINS et al, 2013;SILVEIRA et al, 2014;ABREU et al, 2016). Em função do exposto, objetivamos avaliar in vitro o processo de adesão de macrófagos J774 com arcabouços 3D a base de biopolímero de cana-de-açúcar.…”

Section: Introductionunclassified

Avaliação in Vitro Do Processo De Adesão De Macrófagos J774 Com Arcabouços 3d De Biopolímero De Cana-De-Açúcar

Ferreira¹,

Muniz-Filho²,

Oliveira³

et al. 2017

Blucher Biophysics Proceedings

Self Cite

View full text Add to dashboard

“…Many carriers have been tested experimentally, using scaffolds composed of chitosan-gelatin blends 7 or bioactive glass showing biointegration and remodeling of tissues with features that allow for future applications 10,11 . This study assessed by CT imaging and histology, the ability to osteo-promotion of the association of biopolymer gel as carrier of bone morphogenetic protein and lyophilized bone grafts in the formation of a barrier compared to collagen membrane of bovine origin in the treatment of critical defects in rats calvarium in periods of 90 and 180 days after surgery.…”

Section: Introductionmentioning

confidence: 99%

Hydrogel of polysaccharide of sugarcane molasses as carrier of bone morphogenetic protein in the reconstruction of critical bone defects in rats

Júnior¹,

Carvalho²,

Catunda³

et al. 2013

Acta Cir. Bras.

Self Cite

View full text Add to dashboard

PURPOSE:To evaluate the benefit of using carriers such as the biopolymer gel (hidrogel of polysaccharide of sugarcane molasses) associated with the bone morphogenetic proteins (BMP's) in the repair of critical bone defects in calvaria of Wistar rats. METHODS:Forty-two rats were submitted to a surgical calvaria bone defects. These animals were divided into two experimental groups, positive control group and negative control group. The Group I the calvaria defect was filled up with biopolymer gel, biological membrane, BMP and lyophilized graft. The Group II was treated with biopolymer gel, BMP and lyophilized graft. And the group III (positive control group) was treated with BMP, lyophilized graft and biological membrane. In the negative control group (Group IV) a defect was made in the rat calvaria and the animals were sacrificed immediately after the surgery. The animals of experimental groups and positive control group were slaughtered after subsequent periods of 90 and 180 days. In these periods, the histological analysis and image assessment by cone bean tomographic imaging were obtained. RESULTS:There was highest bone tissue formation with statistically significant results in the groups that associated biopolymer gel and membrane (Group I), followed by the group III (BMP, lyophilized graft and biological membrane). The lower bone formation occurred in the group not using the sugarcane biopolymer gel (Group II). The radiolucent areas of the analyzes of 180 days among the groups studied were respectively, 14.98 mm², 26.65 mm² and 35.81 mm². CONCLUSION:The biopolymer gel showed to be an excellent bone morphogenetic protein carrier, probably by facilitating the controlled release of these proteins in the process of bone repair.

show abstract

Surgarcane biopolymer patch in femoral artery angioplasty on dogs

Abstract: The sugarcane biopolymer membrane can be used as a patch in femoral artery angioplasty on dogs.

Cited by 21 publications

References 16 publications

Comparative study of the areas of osteochondral defects produced in the femoral condyles of rabbits treated with gel of sugarcane biopolymer

Spongy film of cellulosic polysaccharide as a dressing for aphthous stomatitis treatment in rabbits

Avaliação in Vitro Do Processo De Adesão De Macrófagos J774 Com Arcabouços 3d De Biopolímero De Cana-De-Açúcar

Hydrogel of polysaccharide of sugarcane molasses as carrier of bone morphogenetic protein in the reconstruction of critical bone defects in rats

Contact Info

Product

Resources

About