Surfactin/iturin A interactions may explain the synergistic effect of surfactin on the biological properties of iturin A

Surface-Active Properties of Surfactin/Iturin A Mixtures Produced byBacillus subtilis

“…27 The negative and minimum value of the mixing excess free energy for Xs ) 0.4 confirms that the surfactin-C 15 and iturin A-C 15 molecular interaction is maximum in mixed monolayer for Xs ) 0.4, and this interaction is very strong when the mixed monolayer is highly condensed. This result is consistent with previous findings, 16 which indicated a maximum negative deviation from the additivity rule in the mean molecular area of surfactin/iturin A mixed monolayers for Xs ) 0.4. Similarly, the negative deviations of cmc from the additivity rule and X 1 M values clearly indicate the formation of surfactin-C 15 /iturin A-C 15 mixed micelles for Xs ) 0.2 and 0.4.…”

Surface-Active Properties of Surfactin/Iturin A Mixtures Produced byBacillus subtilis

“…27 The negative and minimum value of the mixing excess free energy for Xs ) 0.4 confirms that the surfactin-C 15 and iturin A-C 15 molecular interaction is maximum in mixed monolayer for Xs ) 0.4, and this interaction is very strong when the mixed monolayer is highly condensed. This result is consistent with previous findings, 16 which indicated a maximum negative deviation from the additivity rule in the mean molecular area of surfactin/iturin A mixed monolayers for Xs ) 0.4. Similarly, the negative deviations of cmc from the additivity rule and X 1 M values clearly indicate the formation of surfactin-C 15 /iturin A-C 15 mixed micelles for Xs ) 0.2 and 0.4.…”

Antifungal activity and gene expression of lipopeptide antibiotics in strains of genus Bacillus

“…Lg 37s. Therefore, the difference in antifungal activity of the tested Bacillus strains is probably associated with the expression and subsequent synthesis of a wider spectrum of antibiotic compounds, and their simultaneous fungitoxic action (additive effect), which is in line with literature data [8].…”

Food safety and biological control; genomic insights and antimicrobial potential of Bacillus velezensis FB2 against agricultural fungal pathogens

“…By combining the results of antifungal activity shown by crude extract, and ESI-MS analysis showing the presence of surfactin and iturin, this could be inferred that either both of these compounds have their own activities or they may be acting synergistically to inhibit tested fungal growth. The latter observation is in agreement with the previous studies which proposed that surfactin does not have antimicrobial activity by its own, but rather acts synergistically with iturin or other metabolites for enhance antimicrobial activity [56,57]. In another study, a crude extract of Bacillus velezensis DTU001 has been found more effective as compared to individual antifungal compounds (iturins and fengycins) [2].…”

Surface-Active Properties of Surfactin/Iturin A Mixtures Produced byBacillus subtilis

“…27 The negative and minimum value of the mixing excess free energy for Xs ) 0.4 confirms that the surfactin-C 15 and iturin A-C 15 molecular interaction is maximum in mixed monolayer for Xs ) 0.4, and this interaction is very strong when the mixed monolayer is highly condensed. This result is consistent with previous findings, 16 which indicated a maximum negative deviation from the additivity rule in the mean molecular area of surfactin/iturin A mixed monolayers for Xs ) 0.4. Similarly, the negative deviations of cmc from the additivity rule and X 1 M values clearly indicate the formation of surfactin-C 15 /iturin A-C 15 mixed micelles for Xs ) 0.2 and 0.4.…”

Antifungal activity and gene expression of lipopeptide antibiotics in strains of genus Bacillus

“…Lg 37s. Therefore, the difference in antifungal activity of the tested Bacillus strains is probably associated with the expression and subsequent synthesis of a wider spectrum of antibiotic compounds, and their simultaneous fungitoxic action (additive effect), which is in line with literature data [8].…”

Food safety and biological control; genomic insights and antimicrobial potential of Bacillus velezensis FB2 against agricultural fungal pathogens

“…By combining the results of antifungal activity shown by crude extract, and ESI-MS analysis showing the presence of surfactin and iturin, this could be inferred that either both of these compounds have their own activities or they may be acting synergistically to inhibit tested fungal growth. The latter observation is in agreement with the previous studies which proposed that surfactin does not have antimicrobial activity by its own, but rather acts synergistically with iturin or other metabolites for enhance antimicrobial activity [56,57]. In another study, a crude extract of Bacillus velezensis DTU001 has been found more effective as compared to individual antifungal compounds (iturins and fengycins) [2].…”

Surface-Active Properties of Surfactin/Iturin A Mixtures Produced byBacillus subtilis

“…27 The negative and minimum value of the mixing excess free energy for Xs ) 0.4 confirms that the surfactin-C 15 and iturin A-C 15 molecular interaction is maximum in mixed monolayer for Xs ) 0.4, and this interaction is very strong when the mixed monolayer is highly condensed. This result is consistent with previous findings, 16 which indicated a maximum negative deviation from the additivity rule in the mean molecular area of surfactin/iturin A mixed monolayers for Xs ) 0.4. Similarly, the negative deviations of cmc from the additivity rule and X 1 M values clearly indicate the formation of surfactin-C 15 /iturin A-C 15 mixed micelles for Xs ) 0.2 and 0.4.…”

Antifungal activity and gene expression of lipopeptide antibiotics in strains of genus Bacillus

“…Lg 37s. Therefore, the difference in antifungal activity of the tested Bacillus strains is probably associated with the expression and subsequent synthesis of a wider spectrum of antibiotic compounds, and their simultaneous fungitoxic action (additive effect), which is in line with literature data [8].…”

Food safety and biological control; genomic insights and antimicrobial potential of Bacillus velezensis FB2 against agricultural fungal pathogens

“…By combining the results of antifungal activity shown by crude extract, and ESI-MS analysis showing the presence of surfactin and iturin, this could be inferred that either both of these compounds have their own activities or they may be acting synergistically to inhibit tested fungal growth. The latter observation is in agreement with the previous studies which proposed that surfactin does not have antimicrobial activity by its own, but rather acts synergistically with iturin or other metabolites for enhance antimicrobial activity [56,57]. In another study, a crude extract of Bacillus velezensis DTU001 has been found more effective as compared to individual antifungal compounds (iturins and fengycins) [2].…”