Surface properties of Ce-TZP/Al2O3 composite ceramics by coating mesoporous bioactive glass

Yin, Zhihui; Jiang, Feng; Luan, Jiapan; Zhou, Xiang; Wu, Zhenlong; Li, Mingming; Hong, Zhongrong

doi:10.1016/j.compositesb.2019.01.068

Cited by 25 publications

(9 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In vitro studies have been carried out on BGs of different types, namely, 45S5, 55 , 90 − 94 Kokubo glass (N25C25S50, hereafter abbreviated as K50S), 92 , 95 , 96 MBGs, 74 , 81 , 85 , 93 , 97 − 102 13-93, 103 − 105 and other BGs 106 − 111 doped with different amounts of cerium and synthesized by melt-quenching, 54 , 55 , 91 − 93 , 96 , 106 , 108 − 110 , 112 , 113 sol–gel, 100 , 103 , 105 , 107 , 111 , 114 , 115 and sol–gel EISA 72 , 80 , 81 , 97 − 99 , 101 , 102 , 116 methods.…”

Section: Properties Of Bioactive Glassesmentioning

confidence: 99%

Section: Properties Of Bioactive Glassesmentioning

confidence: 99%

“…Table 1 reports the features of the Ce-BGs studied for their bioactivity as a function of compositions, dimensions and shape (not always reported), synthetic methods, and maximum soaking time in simulated body fluid (SBF). 89 In vitro studies have been carried out on BGs of different types, namely, 45S5, 55,90−94 Kokubo glass (N25C25S50, hereafter abbreviated as K50S), 92,95,96 MBGs, 74,81,85,93,97−102 13-93, 103−105 and other BGs 106−111 doped with different amounts of cerium and synthesized by melt-quenchi n g , 5 4 , 5 5 , 9 1 − 9 3 , 9 6 , 1 0 6 , 1 0 8 − 1 1 0 , 1 1 2 , 1 1 3 s o l − g e l , 1 0 0 , 1 0 3 , 1 0 5 , 1 0 7 , 1 1 1 , 1 1 4 , 1 1 5 a n d s o l − g e l EISA 72,80,81,[97][98][99]101,102,116 methods.…”

Section: Mesoporous Glasses (Mbgs)mentioning

confidence: 99%

“…In summary, the presence of cerium does not inhibit HCA formation but can delay it at high concentrations due to the competitive cerium phosphate phase, sometimes identified as CePO 4 . 70,71,[82][83][84]86,87,102 In order to manufacture BGs with higher bioactivity, a suitable morphology can be selected. Some authors 38,116,119,120 used Ce-MBGs as a bioactive filler in alginate beads to increase their bioactivity and pro-osteogenic activity.…”

Section: Mesoporous Glasses (Mbgs)mentioning

confidence: 99%

See 3 more Smart Citations

Cerium Containing Bioactive Glasses: A Review

Zambon

Malavasi

Pallini

et al. 2021

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

Bioactive glasses (BGs) for biomedical applications are doped with therapeutic inorganic ions (TIIs) in order to improve their performance and reduce the side effects related to the surgical implant. Recent literature in the field shows a rekindled interest toward rare earth elements, in particular cerium, and their catalytic properties. Cerium-doped bioactive glasses (Ce-BGs) differ in compositions, synthetic methods, features, and in vitro assessment. This review provides an overview on the recent development of Ce-BGs for biomedical applications and on the evaluation of their bioactivity, cytocompatibility, antibacterial, antioxidant, and osteogenic and angiogenic properties as a function of their composition and physicochemical parameters.

show abstract

Section: Properties Of Bioactive Glassesmentioning

confidence: 99%

Section: Properties Of Bioactive Glassesmentioning

confidence: 99%

Section: Mesoporous Glasses (Mbgs)mentioning

confidence: 99%

Section: Mesoporous Glasses (Mbgs)mentioning

confidence: 99%

See 2 more Smart Citations

Cerium Containing Bioactive Glasses: A Review

Zambon

Malavasi

Pallini

et al. 2021

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

show abstract

“… 11 Zhang et al used a mesoporous bioactive glass coating to increase the bioactivity of Ce-TZP/Al 2 O 3 ceramics. 12 …”

Section: Introductionmentioning

confidence: 99%

Mechanical Biocompatibility, Osteogenic Activity, and Antibacterial Efficacy of Calcium Silicate–Zirconia Biocomposites

2021

View full text Add to dashboard Cite

Zirconia ceramics with high mechanical properties have been used as a load-bearing implant in the dental and orthopedic surgery. However, poor bone bonding properties and high elastic modulus remain a challenge. Calcium silicate (CaSi)-based ceramic can foster osteoblast adhesion, growth, and differentiation and facilitate bone ingrowth. This study was to prepare CaSi-ZrO 2 composites and evaluate their mechanical properties, long-term stability, in vitro osteogenic activity, and antibacterial ability. The Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) bacteria and human mesenchymal stem cells (hMSCs) were used to evaluate the antibacterial and osteogenic activities of implants in vitro, respectively. Results indicated that the three-point bending strength of ZrO 2 was 486 MPa and Young’s modulus was 128 GPa, which were much higher than those of the cortical bone. In contrast, the bending strength and modulus of 20% (201 MPa and 48 GPa, respectively) and 30% CaSi (126 MPa and 20 GPa, respectively) composites were close to the reported strength and modulus of the cortical bone. As expected, higher CaSi content implants significantly enhanced cell growth, differentiation, and mineralization of hMSCs. It is interesting to note the induction ability of CaSi in osteogenic differentiation of hMSCs even when cultured in the absence of an osteogenic differentiation medium. The composite with the higher CaSi contents exhibited the greater bacteriostatic effect against E. coli and S. aureus . In conclusion, the addition of 20 wt % CaSi can effectively improve the mechanical biocompatibility, osteogenesis, and antibacterial activity of ZrO 2 ceramics, which may be a potential choice for load-bearing applications.

show abstract