Surface Microscopy of Pigmented Basal Cell Carcinoma

Abstract

To describe the relevant morphologic features and to create a simple diagnostic method for pigmented basal cell carcinoma (BCC) using in vivo cutaneous surface microscopy (ie, dermoscopy, dermatoscopy, or oil epiluminescence microscopy).Design: Pigmented skin lesions were photographed in vivo using immersion oil (surface microscopy). All pigmented skin lesions were excised and reviewed for histological diagnosis. Photographs of 142 pigmented BCCs, 142 invasive melanomas, and 142 benign pigmented skin lesions were randomly divided into 2 equally sized training and test sets. Images from the training set were scored for 45 surface microscopy features. From this a model was derived and tested on the independent test set.

Pigmented reticular structures in basal cell carcinoma and collision tumours

“…In the present study, pigment network or pigment network‐like structures were identified in 3·4% of 412 histopathologically proven BCC lesions. These results are consistent with a previous observation of pigment network in 2·8% of BCCs 5 …”

Value of Dermoscopy in a Population-Based Screening Sample by Dermatologists

“…In accordance with other studies, we observed that dermoscopy significantly increases sensitivity for malignant lesions [1][2][3][4]6]. However, this results also in a small but sig- ing showed no change, hence suggesting that these lesions have a benign behavior.…”

Evaluation of dermoscopic and histopathologic features and their correlations in pigmented basal cell carcinomas

“…However, in the dermis, melanin can either be found in melanophages or lie free. Studies reported that melanin might also be found in hyperplastic epidermal melanocytes in the overlying epidermis 1,2,11 . In our study, we observed varying amounts of pigmentation in all lesions through dermoscopy, and found melanin within basaloid tumour nests, in tumour stroma and in epidermal hyperplastic melanocytes, which is compatible with the data reported in literature.…”

“…Studies reported that melanin might also be found in hyperplastic epidermal melanocytes in the overlying epidermis. 1,2,11 In our study, we observed varying amounts of pigmentation in all lesions through dermoscopy, and found melanin within basaloid tumour nests, in tumour stroma and in epidermal hyperplastic melanocytes, which is compatible with the data reported in literature. In our study, while some dermoscopic features could not be confirmed histopathologically, dermoscopic counterparts of some histopathological findings could not be seen dermoscopically.…”