Surface fluorination of PEEK film by selective wet-chemistry

Surface modification of poly(aryl ether ether ketone) (PEEK) film by covalent coupling of amines and amino acids through a spacer arm

“…19,20 Using the wet-chemistry technique, 21 we have already prepared and characterized a reduced PEEK film displaying a high density of hydroxyl functions on its surface (sample called PEEK-OH; Scheme 1). 15,16 The PEEK-OH reactivity has been assayed by direct derivatization with a 3 H-label ( 3 H-acetic anhydride), and by indirect derivatization (activation with p-nitrophenyl chloroformate, then reaction with 3 H-lysine), followed by liquid scintillation counting ( LSC ) of the sampleassociated radioactivity. 15 The PEEK-OH film has been designed as a versatile starting metarial for the development of several fluorination processes.…”

“…15 The PEEK-OH film has been designed as a versatile starting metarial for the development of several fluorination processes. 16 In this article, we further describe the use of PEEK-OH as a key-intermediate 22,23 for the coupling of a a-v-bifunctional spacer arm allowing the covalent anchorage of various molecules of interest. Our objectives are (a) to display amine and/or carboxyl functions on the PEEK surface (Bornem, Belgium) an used as received.…”

“…After were individually placed in 20 mL polyethylene vials (Milli-Q 20, Packard, San Diego, CA) and 5 this treatment, the contact angle of water was 89Њ ({1Њ). 16 From XPS analysis we found an atomic mL of Aqualuma or Lipoluma cocktails (Lumac, Basel, Switzerland) were added to each vial. A O/C ratio of 0.148, close to the theoretical value 16 ; C 1s (87.13%): 284.8 eV (C{C, C{H), 286.4 eV tri-Carb 1600 TR liquid scintillation analyzer (Packard Instruments, San Diego, CA) was used.…”

“…The PEEK-NCO film (disk of 1.13 cm 2 ) was treated under stirring with a 0.1 M solution of trifluoroethylamine in toluene (20 mL), during PEEK-OH 15, 16 5 h at 20ЊC. The disk was rinsed with toluene (5 DMSO (1.2 L) and sodium borohydride (2.4 g) mL, 15 min), then with acetone (5 mL, 15 min) were introduced in the reaction flask and heated and with PBS buffer containing 0.1% of Triton Xat 120ЊC under stirring (dissolution occurred).…”

Surface functionalization of PEEK films studied by time-of-flight secondary ion mass spectrometry and x-ray photoelectron spectroscopy

“…43 The tagging of PEEK-OH 6 with DAST gave the PEEK-F Ðlm (Scheme 1) ; XPS analysis showed an F/C atomic ratio of 0.0388, corresponding to 74% of derivatization. 43 The ToF-SIMS analyses of the PEEK-OH 1È3 samples have been performed. The di †erences between the native PEEK and the reduced polymers appear somewhat tenuous.…”