Surdosage ou hypersensibilité à la vitamine D ?

Hmami, F.; Oulmaati, A.; Amarti, A.; Kottler, Marie‐Laure; Bouharrou, A.

doi:10.1016/j.arcped.2014.06.025

Cited by 10 publications

(7 citation statements)

References 13 publications

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“…There is a clear risk of vitamin D toxicity arising in these patients as there are several different treatment regimens and monitoring schedules, compounded by a lack of age‐specific guidance . A recent French case series of nine children who presented with severe hypercalcaemia following a cumulative dose of 600 000 units also indicated the need to adhere to current recommended vitamin D doses . There is also a case of megadoses of vitamin D being used inappropriately by an alternative health practitioner, resulting in patient harm .…”

Section: Resultsmentioning

confidence: 99%

A review of the growing risk of vitamin D toxicity from inappropriate practice

Taylor

Davies

2018

Brit J Clinical Pharma

134

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Vitamin D is a particularly important sterol hormone, with evidence emerging of its beneficial effects well beyond bone. In consequence of this and increased global recognition of vitamin D deficiency in the general population, there has been a resurgence in treatment with vitamin D preparations. However, the increasing use of vitamin D treatments has also seen a substantial increase in the number of reports of vitamin D intoxication, with the majority (75%) of reports published since 2010. Many of these cases are a consequence of inappropriate prescribing, and the use of high-dose over-the-counter preparations or unlicensed preparations. This review highlights that the majority of cases were preventable and discusses the inappropriate use of poorly formulated, and unlicensed vitamin D preparations.

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Section: Resultsmentioning

confidence: 99%

A review of the growing risk of vitamin D toxicity from inappropriate practice

Taylor

Davies

2018

Brit J Clinical Pharma

134

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“…For people who are at risk of vitamin deficiencies, vitamin supplementation is regarded as an effective treatment (e.g., intake of multivitamin tablets). However, an overdose of vitamins can be toxic in nature [ 16 , 17 , 18 , 19 , 20 ]. In addition, interactions of vitamins and other drugs are often reported [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

A Review of the Extraction and Determination Methods of Thirteen Essential Vitamins to the Human Body: An Update from 2010

et al. 2018

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Vitamins are a class of essential nutrients in the body; thus, they play important roles in human health. The chemicals are involved in many physiological functions and both their lack and excess can put health at risk. Therefore, the establishment of methods for monitoring vitamin concentrations in different matrices is necessary. In this review, an updated overview of the main pretreatments and determination methods that have been used since 2010 is given. Ultrasonic assisted extraction, liquid–liquid extraction, solid phase extraction and dispersive liquid–liquid microextraction are the most common pretreatment methods, while the determination methods involve chromatography methods, electrophoretic methods, microbiological assays, immunoassays, biosensors and several other methods. Different pretreatments and determination methods are discussed.

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“…Currently, the safety concerns restrict the use of bisphosphonates in children for VDI treatment . We therefore focused on the safety of bisphosphonate treatment in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…Despite reported success of bisphosphonates in the treatment of VDI, current reviews on bisphosphonate use in children emphasize that glucocorticoids are the treatment of choice for vitamin D‐induced hypercalcemia . Moreover, although glucocorticoids have serious adverse effects in children (particularly with prolonged use), prednisolone treatment for VDI is still preferred by some clinicians due to safety concerns about bisphosphonate use in children . Lack of sufficient data on the efficacy of bisphosphonates compared with prednisolone may be contributing to the restricted use of bisphosphonates in pediatric VDI.…”

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confidence: 99%