Supratentorial cortical ependymoma: An unusual presentation of a rare tumor

Abstract

Ependymomas are glial tumors derived from ependymal cells lining the ventricles and the central canal of the spinal cord. Two thirds of ependymomas arise in the infratentorial or intraventricles, whereas one-third are located in supratentorial space. But supratentorial “cortical” ependymomas are very rare. We report a case of a cortical ependymoma in a 17-year-old boy. The patient presented with transient recurrent right weakness and diplopia. This tumor was located in the left parieto-occipital region and he had gross total excision. Microscopy and immunohistochemistry showed grade III differentiation ependymoma.

Supra-Tentorial Cortical Ependymoma in an Adult: Case Report and Review of the Literature

“…larger in size at the time of diagnosis with a 94% of supratentorial ependymomas manifest with a size larger than 4 cm and often contain a mixed solid and cystic component as described by Roncaroli et al [1] [2]. A plain CT of CE ranges from iso to hypo-dens.…”

“…Treatment is similar to the classical (intra-ventricular) ependymomas. Complete surgical resection is the treatment of choice followed by radiation therapy for both low and high grade CEs [1] [2]. Chemotherapy is given to children below the age of three after incomplete resection of the tumor to delay or avoid irradiation [1] [2].…”

“…Ependymomas are glial tumors derived from ependymal cells lining the ventricles and the central canal [1] [2]. They are most frequently seen in pediatrics and young adults.…”

“…Supra-tentorial cortical ependymomas (CE) are very rare type of ependymoma with a few reported cases in the literatures [1] [2]. They occur in the superficial cortex and have no connection with the ventricular lining [1] [4].…”

Evolución y Tasa de Recuperación en el Tratamiento Ependimoma Cortical. Relato de caso

“…Ependymomas are rare central nervous system (CNS) tumors 1 that arise from differentiated ependymal cells located in the ventricular system, choroid plexus, and along the central canal of spinal cord 2,3 . Representing 2% to 9% of all neuroepithelial tumors 3,7 it may manifest at all ages, affecting more frequently children and young adults 1,4,7 ; with no gender predilection 3 .…”