1992
DOI: 10.1271/bbb.56.1162
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Suppression of Hydrogen Peroxide-induced Mammalian Cytotoxicity by Nordihydroguaiaretic Acid

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Cited by 23 publications
(17 citation statements)
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“…A small amount of H 2 O 2 was detected in aqueous solutions of polyphenols with a catechol moiety or a galloyl moiety, e.g. (+)-catechin, quercetin and methyl gallate in this and previous papers (Long et al , 2000;Nakayama et al , 1995;Miura et al , 1998;Kajiya et al , 2001), but these compounds inhibited the cytotoxic effects of H 2 O 2 in the cells (Nakayama et al , 1992b;Nakayama et al , 1993). We assume that higher amounts of these compounds were incorporated into the cells during incubation and less H 2 O 2 was produced in the medium than the compounds with a gallyl moiety.…”
Section: Discussionsupporting
confidence: 50%
“…A small amount of H 2 O 2 was detected in aqueous solutions of polyphenols with a catechol moiety or a galloyl moiety, e.g. (+)-catechin, quercetin and methyl gallate in this and previous papers (Long et al , 2000;Nakayama et al , 1995;Miura et al , 1998;Kajiya et al , 2001), but these compounds inhibited the cytotoxic effects of H 2 O 2 in the cells (Nakayama et al , 1992b;Nakayama et al , 1993). We assume that higher amounts of these compounds were incorporated into the cells during incubation and less H 2 O 2 was produced in the medium than the compounds with a gallyl moiety.…”
Section: Discussionsupporting
confidence: 50%
“…), thus preserving the quality of fresh fruit during storage and extending shelf-life by delaying fruit senescence (Connor et al 2002, Ehsani-Moghaddam et al 2006, Schijlen et al 2006, Ehsani-Moghaddam et al 2008. Polyphenols, which are important antioxidants with high reactive activity, exhibit positive effects on human health in terms of anticarcinogenic and antiatherogenic activities (Middleton Jr and Kandaswami 1992, Nakayama 1994, Decker 1995. Titratable acidity expressed as percent citric acid equivalent (% citric acid equiv.…”
Section: Resultsmentioning
confidence: 99%
“…Therefore, abolition of H 2 O 2 is needed to protect body as well as food systems. Polyphenols, found in the dietary source, can protect mammalian and bacterial cells from cytotoxicity induced by H 2 O 2 [32] . Therefore, the phenolic compound of the AHE is involved in removing the H 2 O 2 .…”
Section: Discussionmentioning
confidence: 99%