Supplementation of diets for Santa Ines sheep with organic and inorganic zinc sources

Vilela, Flávio Garcia; Zanetti, Marcus Antônio; Netto, Arlindo Saran; Júnior, José Esler de Freitas; Rennó, Francisco Palma; Venturelli, Beatriz Conte; Canaes, Taíssa de Souza

doi:10.1590/s1516-35982012000900023

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…The study findings indicate that Zn supplementation at 300 mg/kg DM, a concentration well-tolerated by sheep [36,37], is useful for preventing excessive hepatic Cu accumulation in sheep exposed to high dietary concentrations of Cu.…”

Section: Discussionmentioning

confidence: 99%

Dietary Zinc Supplementation to Prevent Chronic Copper Poisoning in Sheep

Minervino

López‐Alonso

Júnior

et al. 2018

Animals

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Simple SummarySheep are susceptible to copper toxicosis, a deadly disease that usually occurs when the animals ingest large amounts of this mineral. Considering that the susceptibility of sheep to copper accumulation varies widely among breeds and from animal to animal., we evaluate whether Zn supplementation could be an option as a preventive measure to protect against hepatic Cu accumulation in sheep. Zn at 300 mg/kg dry matter (DM) is useful for preventing excessive hepatic Cu accumulation. Hepatic Cu accumulation is lower in animals receiving the Zn supplementation.AbstractThe aim of this study was to evaluate whether zinc (Zn) supplementation protects against hepatic copper (Cu) accumulation in copper-loaded sheep. Forty cross-bred lambs were assigned to five experimental groups. These included the control group (C) and four treatment groups that received Cu and/or Zn supplementation (dry matter (DM) basis) over 14 weeks, as follows: Cu (450 mg Cu/kg); Zn-35 (450 mg Cu + 35 mg Zn/kg); Zn-150 (450 mg Cu + 150 mg Zn/kg); and Zn-300 (450 mg Cu + 300 mg Zn/kg). Blood, liver, and bile samples were obtained for mineral determination by inductively coupled plasma optical emission spectrometry (ICP–OES). The hepatic metallothionein (MT) concentrations were also determined. At the end of the experiment, hepatic Cu concentrations were higher in all Cu-supplemented groups than in C. Hepatic Cu accumulation was lower in the groups receiving the Zn supplementation than in the Cu group, although the difference was only statistically significant (66%) in the Zn-300 group. The MT concentrations tended to be higher (almost two-fold) in the Zn groups (but were not dose related) than in the C and Cu groups, and they were related to hepatic Zn concentrations. Zn supplementation at 300 mg/kg DM is useful for preventing excessive hepatic Cu accumulation in sheep exposed to high dietary concentrations of Cu.

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Section: Discussionmentioning

confidence: 99%

Dietary Zinc Supplementation to Prevent Chronic Copper Poisoning in Sheep

Minervino

López‐Alonso

Júnior

et al. 2018

Animals

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“…In one experiment (Henry et al, 1997) zinc concentrations as high as 2100 mg/kg were fed for as long as 30 days without reducing feed intake, but tissues were not examined for histological lesions. Recent studies in Brazil indicate that feeding weaning lambs diets supplemented with zinc at 200, 400 and 600 mg/kg (information on zinc concentration in the basal diet was not available) from different sources (zinc oxide, zinc proteinate and zinc amino acid) for 114 days did not cause any negative effects on animal performance (Vilela et al, 2012). Wang et al (2006) did not find any significant difference in body weight gain and feed to gain between lambs given different levels of zinc supplementation (50, 100 and 150 mg/kg diet) for 70 days; zinc content in basal diet was 16 mg/kg feed.…”

Section: Ruminantsmentioning

confidence: 99%

Scientific Opinion on the potential reduction of the currently authorised maximum zinc content in complete feed

Högstrand¹

2014

EFS2

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A critical review of (i) the zinc requirements of food-producing and pet animals, (ii) the zinc concentration of feed materials and (iii) the calculated background zinc concentration of complete feed supports the possibility of a considerable reduction of the currently authorised maximum concentration for total zinc in feed. The FEEDAP Panel developed, based on an approximation using zinc requirements and background data, potential new maximum contents, which could replace the current ones. The newly proposed total maximum contents are: 150 mg Zn/kg complete feed for piglets, sows, rabbits, salmonids, cats and dogs; 120 mg Zn/kg complete feed for turkeys for fattening; 100 mg Zn/kg complete feed for all other species and categories. The use of phytase in feeding piglets, pigs for fattening and sows would allow a further reduction of the newly proposed total maximum contents by 30 % (from 150 to 110 mg Zn/kg feed for piglets and sows and from 100 to 70 mg Zn/kg feed for pigs for fattening). The newly proposed total maximum contents ensure health, welfare and productivity of the target species and do not affect consumer safety. The FEEDAP Panel expects that the introduction of the newly proposed total maximum contents, provided they are applied in feeding practices, would result in an overall reduction of zinc emissions from animal production of about 20 %. Zinc in Feed, including Noël A. Dierick, Jürgen Gropp, Catherine Jondreville, Marta Lopez Alonso, Anne Katrine Lundebye, Wolfgang Maret and Patrick Schlegel for the preparatory work on this scientific opinion. The Panel also wishes to thank the Authorities of EU Member States and EEA/EFTA countries, and stakeholders who provided information following a call for data on zinc in animal nutrition launched by EFSA. 4 An editorial amendment was carried out on section 6.3 that does not materially affect the contents nor outcome of this Scientific Opinion. To avoid confusion, the original version has been removed from the EFSA Journal, but is available on request, as is a version showing all the changes made. SUMMARYFollowing a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the potential reduction of the currently authorised maximum zinc content in complete feed (250 mg Zn/kg for pet animals, 200 mg Zn/kg for fish and milk replacer and 150 mg Zn/kg for other animal species).To improve the available information on the use of zinc in animal nutrition, EFSA launched a call for data to EU Member States and EEA/EFTA countries and to stakeholders. The data submitted were used in the current Scientific Opinion.Zinc in the form of its divalent metal ion, Zn 2+ , is nutritionally essential for all living organisms. The total amount of zinc in the human body is 2−3 g and its concentrations in tissues are about the same in all mammals. Virtually all its functions are in proteins, in which it is a catalytic, structural, or regulatory cofactor.A critical revi...

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Supplementation of diets for Santa Ines sheep with organic and inorganic zinc sources

Cited by 2 publications

References 12 publications

Dietary Zinc Supplementation to Prevent Chronic Copper Poisoning in Sheep

Dietary Zinc Supplementation to Prevent Chronic Copper Poisoning in Sheep

Scientific Opinion on the potential reduction of the currently authorised maximum zinc content in complete feed

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