Superporous thermo-responsive hydrogels by combination of cellulose fibers and aligned micropores

Halake, Kantappa; Lee, Jonghwi

doi:10.1016/j.carbpol.2014.01.025

Cited by 35 publications

(29 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In most cases, polymer precursor solutions are frozen and subsequently cryopolymerized through small molecule, [104,[119][120][121] UV, [122][123][124] or radiation [110,118,125] initiated methods; however, physically crosslinked gels have also been reported, [126] including PVA-based anisotropic hydrogels prepared via directional freeze-thawing. [107,109] The direction of ice crystal growth determines the orientation of the pore while the rate of freezing predominantly influences the dimensionality of the aligned structures generated, with slower cooling rates resulting in slower ice crystal growth and ultimately the formation of larger ice platelets and thus larger pores following lyophilization.…”

Section: Wwwadvancedsciencenewscom Wwwadvhealthmatdementioning

confidence: 99%

Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

Hoare

2017

Adv Healthcare Materials

170

168

View full text Add to dashboard Cite

Structured macroporous hydrogels that have controllable porosities on both the nanoscale and the microscale offer both the swelling and interfacial properties of bulk hydrogels as well as the transport properties of “hard” macroporous materials. While a variety of techniques such as solvent casting, freeze drying, gas foaming, and phase separation have been developed to fabricate structured macroporous hydrogels, the typically weak mechanics and isotropic pore structures achieved as well as the required use of solvent/additives in the preparation process all limit the potential applications of these materials, particularly in biomedical contexts. This review highlights recent developments in the field of structured macroporous hydrogels aiming to increase network strength, create anisotropy and directionality within the networks, and utilize solvent‐free or additive‐free fabrication methods. Such functional materials are well suited for not only biomedical applications like tissue engineering and drug delivery but also selective filtration, environmental sorption, and the physical templating of secondary networks.

show abstract

Section: Wwwadvancedsciencenewscom Wwwadvhealthmatdementioning

confidence: 99%

Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

Hoare

2017

Adv Healthcare Materials

170

168

View full text Add to dashboard Cite

show abstract

“…Interestingly, the strong nanofibrous networks and hydrated Al‐ co ‐alginate layers make the NFH hold water over 500 times higher than that of its own weight without collapsing, apparently superior to that of other fibrous hydrogels (Figure i). Additionally, cellulose nanofiber enhanced poly( N ‐isopropyl acrylamide) (PNIPAm) hydrogel with aligned micropores as well as the natural chitosan nanofiber‐reinforced polyacrylamide nanocomposite hydrogels have also been developed by the method of freeze‐drying …”

Section: Strategies To Synthesize Nfhgsmentioning

confidence: 99%

“…Otherwise, the conductivity and pH sensing property could be regulated by changing the ratio and spatial arrangement of PANI nanofibers and PAA. Similarly, based on swelling behavior and volume transition characteristics of the PNIPAm, a new kind of composite NFHGs consisting of PNIPAm hydrogels, microfibrillated cellulose, and aligned micropores were created for the temperature sensing . On the aspect of metal ion sensing, Yuan and co‐workers synthesized a graphitic carbon nitride (g‐C 3 N 4 ) hydrogel by self‐assembly/gelation of g‐C 3 N 4 nanofiber suspension for the detection of Cu 2+ .…”

Section: Applications Of Nfhgsmentioning

confidence: 99%

Nanofiber‐Based Hydrogels: Controllable Synthesis and Multifunctional Applications

Duan

Yan

et al. 2018

Macromol. Rapid Commun.

View full text Add to dashboard Cite

Nanofiber-based hydrogels (NFHGs) prepared by the combination of traditional hydrogels and novel nanofibers have demonstrated great potential in various application fields, owing to their integrated advantages of superhydrophilicity, high water-holding capacity, good biocompatibility, enhanced mechanical strength, and excellent structural tenability. In this review, a comprehensive overview of the structure design and synthetic strategy of NFHGs derived from electrospinning technique, weaving, freeze-drying, 3D printing, and molecular self-assembling method is provided. The widely researched multifunctional applications, primarily involving tissue engineering, drug delivery, sensing, intelligent actuator, and oil/water separation are also presented. Furthermore, some unsolved scientific issues and possible directions for future development of this field are also intensively discussed.

show abstract

“…Numerous trails have been made to prolong the residence time of drugs in the body for a complete absorption, but not many systems have been successfully applied in practice. Numerous approaches were conducted to improve gastric residence include dosage forms such as mucoadhesive or bioadhesive systems , high‐density systems , magnetic systems , super porous hydrogels , raft forming systems , low‐density systems , and floating ion exchange resins . Among these, super porous hydrogel has been a promising one.…”

Section: Introductionmentioning

confidence: 99%

Impact of surfactant on the pore and particle sizes of copolymer (2‐acrylamido‐2‐methylpropane sulfonic acid/acrylamide) nanohydrogels for controlled release of 5‐fluorouracil

Awadallah‐F

El-Wahab

Al-Shafey

2017

Polymer Engineering & Sci

View full text Add to dashboard Cite

Nanohydrogels were prepared from copolymerization of acrylamido-2-methylpropane sulfonic acid (AMPS) and acrylamide (AAm) in presence of sodium lauryl sulfate (SLS). The direct ionizing radiation of c-rays was used to initiate the copolymerization reaction. The different concentrations of SLS, variable irradiation doses, a fixed total monomer concentration, and comonomer composition were used. The features of nanohydrogel were characterized by Fourier transform infrared, thermal gravimetric analysis, and BET surface area analysis of porosity. The results confirmed the structure formation of copoly(AMPS/AAm) nanohydrogels. The SLS concentration affects clearly the pore characteristics and nanoparticle sizes. The nanoparticle and pore size distributions referred to that the pores and nanoparticle formed in wide range of nanoscale. The surface area and pore volume depended basically on the SLS concentration. The gel fraction of nanohydrogels ranged from (98 6 2.3) to (100 6 1.5)%. The nanohydrogels were used in in vitro release of 5-fluorouracil (5-FU) at different simulated fluids. The release profile showed a prolonged release of 5-FU at two different simulated fluids of pHs of 1.2 for simulated gastric fluid and 7.4 for simulated intestinal fluid. The study demonstrated that copoly(AMPS/AAm) nanohydrogel may serve as a promising material for the sustained release of 5-FU in stomach and colon media. POLYM. ENG. SCI., 58:94-102, 2018.

show abstract

Superporous thermo-responsive hydrogels by combination of cellulose fibers and aligned micropores

Cited by 35 publications

References 33 publications

Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

Structured Macroporous Hydrogels: Progress, Challenges, and Opportunities

Nanofiber‐Based Hydrogels: Controllable Synthesis and Multifunctional Applications

Impact of surfactant on the pore and particle sizes of copolymer (2‐acrylamido‐2‐methylpropane sulfonic acid/acrylamide) nanohydrogels for controlled release of 5‐fluorouracil

Contact Info

Product

Resources

About