Supercritical Fractionation of Rosemary Extracts to Improve the Antioxidant Activity

Vicente, G.; García-Risco, Mónica Rodríguez; Fornari, Tiziana; Reglero, Guillermo

doi:10.1002/ceat.201100367

Cited by 26 publications

(8 citation statements)

References 25 publications

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“…The results obtained by Kuo et al [121] corroborate the studies carried out by Vicente et al [89] using rosemary leaves; the authors obtained high CA content in the extract in 1 h of extract ion by SFE. The antio xidant activity o f the extract increased with the ext raction time because the volatile oil is depleted from the vegetal matrix at the beginning of the process, and the phenolic co mpounds, which present higher antioxidant activity, are only later extracted.…”

Section: Supercritical Flui D Extracti On (Sfe)supporting

confidence: 81%

“…Due to these issues, natural antioxidants allowing for the substitution of synthetic antioxidants are the target of many studies [86][87][88][89][90][91]. Boo et al [92] demonstrated high antio xidant activities of natural p ig ments found in onion (Allium cepa L.), red cabbage (Brassica oleracea L.), mu lberry (Morus alba L.), purple sweet potato (Ipomoea batatas L.), yellow paprika (Capsicum annuum L.), red beet (Beta vulgaris L.) and grape (Vitis vinifera L.).…”

Section: Modern Techniques For Extraction Of Antioxidantsmentioning

confidence: 99%

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ObtainingAntioxidants from Botanic Matrices Applying Novel Extraction Techniques

Moraes¹,

Zabot²,

Prado³

et al. 2013

fph

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Botanic matrices are abundant sources of antioxidants which have the capacity to avoid the lipid o xidation of food and present remarkab le health benefits. The natural antioxidants might be obtained applying many extraction techniques. Satisfactory results of obtaining extracts with antio xidant properties and high yields using modern extraction techniques are shown by recent studies. The selection of the suitable technique depends on the desired class of substances to be extracted. In this overview, the advances reached in scientific researches involving natural antio xidants are presented. The advantages and potential applicat ions of four novel ext raction techniques: Supercritical Flu id Ext raction, Pressurized Liquid Extraction, M icro wave Assisted Extraction and Ultrasound Assisted Extraction are discussed, considering the characteristics of the target compounds. These techniques reduce the solvent consumption and abridge the extraction time. Consequently, the process productivity is increased.

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Section: Supercritical Flui D Extracti On (Sfe)supporting

confidence: 81%

Section: Modern Techniques For Extraction Of Antioxidantsmentioning

confidence: 99%

ObtainingAntioxidants from Botanic Matrices Applying Novel Extraction Techniques

Moraes¹,

Zabot²,

Prado³

et al. 2013

fph

View full text Add to dashboard Cite

show abstract

“…In the C 0 2 recirculation device, C 0 2 is condensed (= 5 MPa), pumped up to the desired extraction pressure, and heated to the selected extraction temperature. Based on previous studies (21), extraction was carried out for 6 h at 30 MPa and 313 K. In order to remove the essential oil present in the plant matrix and further concentrate the rosemary antioxidant components, fractionation of the extract was carried out during the first hour of extraction (36). Thus, two different extracts were collected in SI and S2; the fraction obtained in SI was used in this study.…”

Section: Characterization Of Alibirdmentioning

confidence: 99%

“…Among its beneficial biological properties, it is hepatoprotective (1), antidiabetic (4), antioxidant (3,13), antiproliferative (15), antiviral (3), antimicrobial (5), and antidepressant (22). Nevertheless, the most reported beneficial property of rosemary is its antioxidant capacity, which is related to the presence of antioxidant phenolic substances, such as camosol, rosmanol, camosic acid, methyl camosate, and rosmarinic and caffeic acids (14,17,36). Carnosic acid and camosol are the most abundant antioxidant compounds present in the rosemary plant.…”

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confidence: 99%

Acute and Repeated Dose (28 Days) Oral Safety Studies of ALIBIRD in Rats

Anadón¹,

Martínez²,

Arés³

et al. 2013

Journal of Food Protection

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ALIBIRD, a test substance composed of oligosaccharides derived from lactulose, a hydrolysate of a whey protein concentrate, and a supercritical extract of rosemary (1:0.5:0.05), was prepared in the laboratory and evaluated for its safety as a multifunctional food additive. In oral toxicity studies (acute and 28 days repeated dose) using Wistar rats, ALIBIRD was administered in a single oral gavage dose of 2,000 mg/kg of body weight and resulted in no adverse events or mortality; a daily dose of 2,000 mg/kg of body weight for 28 days by gavage also resulted in no adverse effects or mortality. No abnormal clinical signs, behavioral changes, body weight changes, or changes in food and water consumption occurred in either study. There were no changes in hematological and serum chemistry values, organ weights, or gross or histological characteristics. Based on test results, it is concluded that ALIBIRD is well tolerated in rats at an acute and subchronic (28 days) dose of 2,000 mg/kg of body weight.

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“…Boo et al demonstrated high antioxidant activities of natural pigments found in onion 7,8 . Onion (Allium cepa) varieties are rich in quercetin (flavonol).…”

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confidence: 99%

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2013

IJPSR

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ABSTRACT:The onion (Allium cepa L), also known as the bulb onion or common onion, is used as a vegetable and is the most widely cultivated species of the genus Allium. Allium cepa L belongs to the family Lilliaceae. The onion has a wide range of beneficial actions on the body and when eaten (especially raw) on a regular basis will promote the general health of the body. The parameters selected were preliminary phytochemical screening and sedative hypnotic activity by chimney test. The Allium cepa Linn powder was successively extracted with benzene, chloroform, ethylacetate, ethanol and water for the identification of the best solvent. Preliminary phytochemical screening was carried out for all the extracts and maximum chemical constituents were observed in the ethanolic extract. The sedative and hypnotic activity were tested by using ethanolic extract on mice by using chimney test and found to be effective at a dose of mg/kg when compared to the reference standard. In conclusion it can be said that Allium cepa L possess Sedative and hypnotic activity at a dose of mg/kg. INTRODUCTION: A sedative or hypnotic drug is one that reversibly depresses the activity of the central nervous system, used chiefly to induce sleep and to allay anxiety. Recent studies have shown that herbal drugs exert good sedative and hypnotic effect on the central nervous system [1][2][3] . The scientific literature has demonstrated that different extracts and compounds of onion produce significant biological effects 4 . Onion (Allium cepa) bulb from Liliaceae has antioxidant, spasmolytic and antihypertensive activities. Calcium channels were involved in the onion peel hydroalcoholic extract spasmolytic effect on rat ileum. Flavonoids extracted from onion peel improve male sexual function 5,6 .

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Supercritical Fractionation of Rosemary Extracts to Improve the Antioxidant Activity

Cited by 26 publications

References 25 publications

ObtainingAntioxidants from Botanic Matrices Applying Novel Extraction Techniques

ObtainingAntioxidants from Botanic Matrices Applying Novel Extraction Techniques

Acute and Repeated Dose (28 Days) Oral Safety Studies of ALIBIRD in Rats

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