Using the data on the decay D + s → f0(980)π + → K + K − π + , we estimate the amplitude of the process D + s → f0(980) → (K + K − + K 0 K0 ) → a 0 0 (980) π + → ηπ 0 π + , caused by the mixing of a 0 0 (980) and f0(980) resonances that breaks the isotopic invariance due to the K + and K 0 meson mass difference. Effects of the interference of this amplitude with the amplitudes of the main mechanisms responsible for the decay D + s → ηπ 0 π + are analyzed. As such mechanisms, we examine the transition D + s → ηρ + → ηπ 0 π + , which is observed in experiment, and the possible transition D + s → a 0 0 (980)π + + a + 0 (980)π 0 → ηπ 0 π + . It is shown that the rapidly varying phase of the a 0 0 (980) − f0(980) transition amplitude strongly influences the interference curves.