Suicide Risk in Primary Care Patients With Major Physical Diseases

Webb, Roger T.

doi:10.1001/archgenpsychiatry.2011.1561

Cited by 190 publications

(170 citation statements)

References 52 publications

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“…As hypothesised, the APMS participants with multimorbidity exhibited higher risks of suicidal thoughts compared to those with neither physical health nor CMD conditions and, as such, our results support some previous studies on the role of mental and physical illness in suicide risk (Qin et al, 2014;Qin et al, 2013;Ratcliffe et al, 2008;Webb et al, 2012). In a population-based study in Canada, Bolton and colleagues concluded that when mental illness was taken into account, cancer patients compared to patients with other chronic illness had an increased suicide risk 3 months following cancer diagnosis (Bolton et al, 2015).…”

Section: Discussionsupporting

confidence: 91%

“…Furthermore, studies on suicide deaths of people with physical illness diagnoses appear to have an increased prevalence of mental disorders (Henriksson et al, 1995;Qin et al, 2014;Webb et al, 2012). Chronic illnesses like cancer, asthma, musculoskeletal and cardiovascular disease may play a role in the development of suicidal behaviours, varying as a function of the presence of subsequent mental disorder (Bolton et al, 2015;Webb et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…Chronic illnesses like cancer, asthma, musculoskeletal and cardiovascular disease may play a role in the development of suicidal behaviours, varying as a function of the presence of subsequent mental disorder (Bolton et al, 2015;Webb et al, 2012). Perhaps unsurprisingly, numerous studies have found depression to be the most common psychiatric diagnosis among chronic physically ill patients, being associated with a higher suicide risk (Anguiano et al, 2012;Pompili et al, 2012;Pompili et al, 2014;Webb et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…Despite the growing evidence that both mental and physical disorders contribute to suicide risk, very few studies have investigated the extent to which their co-occurrence (multimorbidity) is associated with suicide risk (Goodwin et al, 2003a;Singhal et al, 2014;Qin et al, 2014;Webb et al, 2012). Most of the extant research has focused on comorbidity and suicide risk, with comorbidity defined as a further diagnosis which is secondary to an index condition (Blasco-Fontecilla et al, 2015;Kavalidou et al, 2016;Valderas et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

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The role of physical and mental health multimorbidity in suicidal ideation

Kavalidou

Smith

O’Connor

2017

Journal of Affective Disorders

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The role of physical and mental health multimorbidity in suicidal ideation

Kavalidou

Smith

O’Connor

2017

Journal of Affective Disorders

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“…The difference between these two groups regarding a self-reported lifetime history of suicide attempts was even more pronounced and significant (15.0% for COPD patients, 6.6% for subjects without COPD; OR52.29). According to a large case-control study [44] the relative risk of suicide was significantly elevated among patients with COPD compared with patients without major chronic illnesses (3.1% versus 1.9%, respectively; OR51.80).…”

Section: Suicidality In Patients With Copdmentioning

confidence: 99%

Depression and suicidality in COPD: understandable reaction or independent disorders?

Hegerl

Mergl

2014

European Respiratory Journal

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Both depression and chronic obstructive pulmonary disease (COPD) are prevalent, severe and often comorbid disorders. There is a risk of undertreatment for depression in patients with COPD as depressive symptoms, including suicidal tendencies, can erroneously be conceptualised as an understandable reaction to COPD and not as signs of an independent depressive disorder. In this context, the comorbidity rates of COPD and depression, the risk of suicidal behaviour in patients with COPD, and the evidence base for pharmaco-and psychotherapy in these patients are reviewed.Because symptoms of depression and COPD overlap it remains unclear how far the prevalence of major depression in COPD exceeds that in the general population. The suicide risk appears to be increased in COPD. Methodological studies providing evidence for the antidepressant efficacy of antidepressants or psychotherapy in patients with COPD are lacking. Recommendations for clinicians on how to separate depression from an understandable reaction to COPD are provided.Given the profound effects of depression on quality of life, life expectancy, COPD prognosis and suicide risk it is important to carefully diagnose and treat depression in patients with COPD according to national guidelines. @ERSpublications Comorbid depression has profound effects on COPD prognosis and should not be seen as understandable reaction to COPD

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Association Between Neurological Disorders and Death by Suicide in Denmark

Erlangsen

Stenager

Conwell

et al. 2020

JAMA

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IMPORTANCE Neurological disorders have been linked to suicide, but the risk across a broad spectrum of neurological disorders remains to be assessed.OBJECTIVES To examine whether people with neurological disorders die by suicide more often than other people and to assess for temporal associations. DESIGN, SETTING, AND PARTICIPANTSNationwide, retrospective cohort study on all persons 15 years or older living in Denmark, from 1980 through 2016 (N = 7 300 395).EXPOSURES Medical contact for head injury, stroke, epilepsy, polyneuropathy, diseases of myoneural junction, Parkinson disease, multiple sclerosis, central nervous system infections, meningitis, encephalitis, amyotrophic lateral sclerosis, Huntington disease, dementia, intellectual disability, and other brain diseases from 1977 through 2016 (n = 1 248 252). MAIN OUTCOMES AND MEASURESDeath by suicide during 1980-2016. Adjusted incidence rate ratio (IRRs) were estimated using Poisson regressions, adjusted for sociodemographics, comorbidity, psychiatric diagnoses, and self-harm. RESULTSOf the more than 7.3 million individuals observed over 161 935 233 person-years (49.1% males), 35 483 died by suicide (median duration of follow-up, 23.6 years; interquartile range, 10.0-37.0 years; mean age, 51.9 years; SD, 17.9 years). Of those, 77.4% were males, and 14.7% (n = 5141) were diagnosed with a neurological disorder, equivalent to a suicide rate of 44.0 per 100 000 person-years compared with 20.1 per 100 000 person-years among individuals not diagnosed with a neurological disorder. People diagnosed with a neurological disorder had an adjusted IRR of 1.8 (95% CI, 1.7-1.8) compared with those not diagnosed. The excess adjusted IRRs were 4.9 (95% CI, 3.5-6.9) for amyotrophic lateral sclerosis, 4.9 (95% CI, 3.1-7.7) for Huntington disease, 2.2 (95% CI, 1.9-2.6) for multiple sclerosis, 1.7 (95% CI, 1.6-1.7) for head injury, 1.3 (95% CI, 1.2-1.3) for stroke, and 1.7 (95% CI, 1.6-1.8) for epilepsy. The association varied according to time since diagnosis with an adjusted IRR for 1 to 3 months of 3.1 (95% CI, 2.7-3.6) and for 10 or more years, 1.5 (95% CI, 1.4 to 1.6, P < .001). Compared with those who were not diagnosed with a neurological disorder, those with dementia had a lower overall adjusted IRR of 0.8 (95% CI, 0.7-0.9), which was elevated during the first month after diagnosis to 3.0 (95% CI, 1.9-4.6; P < .001). The absolute risk of suicide for people with Huntington disease was 1.6% (95% CI, 1.0%-2.5%). CONCLUSIONS AND RELEVANCEIn Denmark from 1980 through 2016, there was a significantly higher rate of suicide among those with a diagnosed neurological disorder than persons not diagnosed with a neurological disorder. However, the absolute risk difference was small.

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Suicide Risk in Primary Care Patients With Major Physical Diseases

Cited by 190 publications

References 52 publications

The role of physical and mental health multimorbidity in suicidal ideation

The role of physical and mental health multimorbidity in suicidal ideation

Depression and suicidality in COPD: understandable reaction or independent disorders?

Association Between Neurological Disorders and Death by Suicide in Denmark

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