Suggested standards for reporting on arterial aneurysms

Johnston, K.Wayne; Rutherford, Robert B.; Tilson, M. David; Shah, Dhiraj M.; Hollier, Larry H.; Stanley, James C.

doi:10.1067/mva.1991.26737

Cited by 1,082 publications

(313 citation statements)

References 21 publications

Supporting

Mentioning

288

Contrasting

Unclassified

Order By: Relevance

“…An accepted definition of arterial aneurysm 10 was used. [12][13][14] Patients were identified from surgery records at vascular surgery units and were then contacted; consent was obtained, and family histories were collected.…”

Section: Subjects and Phenotypingmentioning

confidence: 99%

Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13

Shibamura

Olson

Keulen³

et al. 2004

Circulation

116

View full text Add to dashboard Cite

Background-Abdominal aortic aneurysm (AAA) is a relatively common disease, with 1% to 2% of the population harboring aneurysms. Genetic risk factors are likely to contribute to the development of AAAs, although no such risk factors have been identified. Methods and Results-We performed a whole-genome scan of AAA using affected-relative-pair (ARP) linkage analysis that includes covariates to allow for genetic heterogeneity. We found strong evidence of linkage (logarithm of odds [LOD] scoreϭ4.64) to a region near marker D19S433 at 51.88 centimorgans (cM) on chromosome 19 with 36 families (75 ARPs) when including sex and the number of affected first-degree relatives of the proband (N aff ) as covariates. We then genotyped 83 additional families for the same markers and typed additional markers for all families and obtained a LOD score of 4.75 (Pϭ0.00014) with sex, N aff , and their interaction as covariates near marker D19S416 (58.69 cM).We also identified a region on chromosome 4 with a LOD score of 3.73 (Pϭ0.0012) near marker D4S1644 using the same covariate model as for chromosome 19. Conclusions-Our results provide evidence for genetic heterogeneity and the presence of susceptibility loci for AAA on chromosomes 19q13 and 4q31.

show abstract

Section: Subjects and Phenotypingmentioning

confidence: 99%

Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13

Shibamura

Olson

Keulen³

et al. 2004

Circulation

116

View full text Add to dashboard Cite

show abstract

“…These findings suggest that a sensitivity analysis is appropriate when a patient-specific computational study is carried out to obtain a quantitative description of the wall shear stress distribution. than 1.5 times the local diameter of the healthy aorta (Johnston et al 1991), which is approximately 2 cm in the abdominal parts of the aorta. One-fifth of large abdominal aneurysms are not limited to the infrarenal aorta, but also extend into one or both of the common iliac arteries (Armon et al 1998).…”

mentioning

confidence: 92%

Dynamics of pulsatile flow through model abdominal aortic aneurysms

2014

View full text Add to dashboard Cite

To contribute to the understanding of flow phenomena in abdominal aortic aneurysms, numerical computations of pulsatile flows through aneurysm models and a stability analysis of these flows were carried out. The volume flow rate waveforms into the aneurysms were based on measurements of these waveforms, under rest and exercise conditions, of patients suffering abdominal aortic aneurysms. The Reynolds number and Womersley number, the dimensionless quantities that characterize the flow, were varied within the physiologically relevant range, and the two geometric quantities that characterize the model aneurysm were varied to assess the influence of the length and maximal diameter of an aneurysm on the details of the flow. The computed flow phenomena and the induced wall shear stress distributions agree well with what was found in PIV measurements by Salsac et al. (J. Fluid Mech., vol. 560, 2006, pp. 19-51). The results suggest that long aneurysms are less pathological than short ones, and that patients with an abdominal aortic aneurysm are better to avoid physical exercise. The pulsatile flows were found to be unstable to three-dimensional disturbances if the aneurysm was sufficiently localized or had a sufficiently large maximal diameter, even for flow conditions during rest. The abdominal aortic aneurysm can be viewed as acting like a 'wavemaker' that induces disturbed flow conditions in healthy segments of the arterial system far downstream of the aneurysm; this may be related to the fact that one-fifth of the larger abdominal aortic aneurysms are found to extend into the common iliac arteries. Finally, we report a remarkable sensitivity of the wall shear stress distribution and the growth rate of three-dimensional disturbances to small details of the aneurysm geometry near the proximal end. These findings suggest that a sensitivity analysis is appropriate when a patient-specific computational study is carried out to obtain a quantitative description of the wall shear stress distribution.

show abstract

“…Professor Doctor, Division of Radiology, Coordinator of the or heart wall, that is larger than 50% of the presumed normal diameter (1) . Among aortic aneurysms, 90 % to 95% are located in the abdominal aorta below the renal arteries bifurcation (2) .…”

mentioning

confidence: 99%

A importância do diagnóstico por imagem na classificação dos endoleaks como complicação do tratamento endovascular de aneurismas aórticos

et al. 2010

View full text Add to dashboard Cite

OBJECTIVE: To describe a series of endoleak cases and their respective classification. MATERIALS AND METHODS: The authors developed a retrospective study of endoleaks diagnosed at their institution in the period between 2005 and 2009. Twenty cases were included to illustrate the different types of endoleaks. RESULTS: Seventy percent of the patients were men, and the ages ranged from 43 to 91 years (mean, 76.3 years). Thirteen cases were observed in the infrarenal abdominal aorta, four in the thoracic aorta, two in the iliac artery, and one in the carotid territory. Ultrasonography was the method utilized for diagnosis in three cases, and computed tomography in the other 17 cases. 5. Professor Doctor, Division of Radiology, Coordinator of the or heart wall, that is larger than 50% of the presumed normal diameter (1) . Among aortic aneurysms, 90 % to 95% are located in the abdominal aorta below the renal arteries bifurcation (2) .The prevalence of abdominal aortic aneurysms increases with age, affecting approximately 6% of individuals after 65 years of age (3) . The mean age at diagnosis is between 65 and 75 years, with male predominance (4) . Currently, its incidence is increasing as a consequence of the global population aging (5) .Chagas Neto FA, Barreto ARF, Reis HF, Bernardes JPG, Leitão JPC, Lucena AF, Muglia VF, Elias Junior J. The value of diagnostic imaging in the classification of endoleaks as a complication of endoluminal grafting of aortic aneurysms. Radiol Bras. 2010;43(5):289-294.

show abstract

Suggested standards for reporting on arterial aneurysms

Cited by 1,082 publications

References 21 publications

Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13

Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13

Dynamics of pulsatile flow through model abdominal aortic aneurysms

A importância do diagnóstico por imagem na classificação dos endoleaks como complicação do tratamento endovascular de aneurismas aórticos

Contact Info

Product

Resources

About