Successfully treated bilateral xanthogranulomatous pyelonephritis in a child

Hyla-Klekot, Lidia; Paradysz, Andrzej; Kucharska, Grażyna; Lipka, Katarzyna; Zajęcki, Wojciech

doi:10.1007/s00467-008-0821-2

Cited by 5 publications

(2 citation statements)

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“…In most cases extirpation is necessary because the disease results in an infected, nonfunctioning kidney. Nephron-sparing surgery is an option, especially in cases of bilateral disease with demonstrated significant residual functional renal tissues [ 19 ]. Laparoscopic nephrectomy is feasible for some cases of XGP and few cases have been cured by this operative modality and its advantage over radical nephrectomy is being explored.…”

Section: Discussionmentioning

confidence: 99%

Case report: Xanthogranulomutous pyelonephritis presenting as “Wilms’ tumor”

et al. 2016

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BackgroundXanthogranulomatous pyelonephritis (XGP) is a rare renal tumor that arises as a complication of chronic obstructive pyelonephritis of uncertain etiology. It is primarily an adult tumor seen occasionally in children associated with urinary tract obstruction due to congenital urological anomalies, nephrolithiasis, and recurrent urinary tract infections. Radiologically, it may show neoplastic features such as those seen in common pediatric renal malignancies like wilms’ tumor and renal cell carcinoma. This overlap in radiological manifestation frequently leads to misdiagnosis and delay in appropriate intervention. We report a case of a 3 years old boy who presented with history of recurrent urinary tract infections and a left renal mass initially thought to be Wilms’ tumor.Case presentationWe present a case of a 3 years old boy admitted to the Pediatric oncology unit at Muhimbli National Hospital in Dar es Salaam, Tanzania with one year history of recurrent fever and urinary tract infection signs and symptoms refractory to antibiotic therapy. He was eventually found to have a left kidney mass detected at the District hospital by abdominal ultrasound performed to evaluate a flank mass that was felt by his mother. He was then referred to our unit for a suspicion of Wilms’ tumor which finally turned out to be a left kidney Xanthogranulomatous pyelonephritis.He underwent a successful left nephrectomy and was discharged from hospital in a stable clinical condition and remains asymptomatic at the time of submission of this case report.ConclusionThis case report underscores the need for clinicians attending a febrile child with a renal mass that can be confused with common pediatric renal malignancies such as Wilms’ tumor to broaden their differential diagnosis. The case also underlines the significance of individualized patient evaluation because this patient would have otherwise received preoperative chemotherapy under the International Society of Pediatric Oncology (SIOP) guidelines if the diagnosis of Wilms tumor was not ruled out.

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Section: Discussionmentioning

confidence: 99%

Case report: Xanthogranulomutous pyelonephritis presenting as “Wilms’ tumor”

et al. 2016

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“…Shah K and colleagues reported one bilateral XGP child case managed non-surgically [11]. Hyla-Klekot L and colleagues reported one bilateral XGP patient managed by intensive therapy and partial nephrectomy [12].…”

Section: Discussionmentioning

confidence: 99%

Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review

Ding

Wang

et al. 2020

BMC Urol

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Background: Xanthogranulomatous pyelonephritis (XGP) is an uncommon form of chronic pyelonephritis. Most patients of XGP are diffuse in radiology and the clinical features are typical. Case presentation: We present a case of 24-year-old female with the absence of symptoms and normal laboratory examinations. Contrast computed tomography and intravenous pyelography demonstrate infiltrative renal mass and renal cell carcinoma is presumed. Laparoscopic right radical nephrectomy is performed, but the final pathological result shows XGP. Conclusions: As far as we know, this is the first case report of XGP without any symptoms/signs and with normal laboratory examinations. The diagnosis of atypical XGP is challenging and preoperative renal mass biopsy should be considered in special cases.

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