Successful twin pregnancy after orthotopic liver transplantation

Abstract

-Aim -Report of a case of successful twin pregnancy following liver transplantation. Patient and Method -A 42-year-old nulliparous-woman was subjected to an orthotopic liver transplantation due to Budd-Chiari syndrome. Sixteen months after the transplantation, an ultrasonography revealed twin pregnancy. Her prenatal course was uneventful, except for mild arterial hypertension. The immunosuppressive agents used during pregnancy were cyclosporine and prednisone. Result -The patient gave birth to two healthy girls at 37 weeks of gestation. The patient's postpartum course was uneventful with normal liver and renal function tests. Conclusion -Following successful pregnancy, women may become pregnant and give birth to normal children, including twins HEADINGS -Liver transplantation. Pregnancy, multiple. Hepatic vein thrombosis. Liver disease.

Pregnancy in women with known and treated Budd–Chiari syndrome: Maternal and fetal outcomes

“…Among pregnancies reaching gestation week 20 in our series, preterm delivery was common (76%; 95% confidence interval, 56-97%). However, except for one stillbirth, the fetal outcome was relatively good, which is consistent with literature data in women with known BCS [9][10][11]13,14,16]. Out of 10 previously reported cases, there were 9 moderately preterm or term deliveries with healthy infants and one early preterm delivery of an infant who died 2 days later.…”

“…However, these women could be at risk of developing severe exacerbation of their disease during pregnancy [7,8]. As available reports on pregnancy in women with known BCS are scarce, it is unclear whether or not pregnancy should be contraindicated in patients with known and treated BCS [9][10][11][12][13][14][15][16]. This prompted us to assess the fetal and maternal outcome in a group of women with a desire for pregnancy and who became pregnant after BCS had been recognized and treated.…”

Case of Budd–Chiari syndrome 3 months after vaginal delivery

“…There is no well‐acknowledged consensus concerning clinical criteria to assess the risks of further pregnancy in patients with a history of Budd–Chiari syndrome as far as we know, although some cases reports of successful pregnancies were reported after treatment of Budd–Chiari syndrome, such as liver transplantation 18,19 and portosystemic shunt 20 …”

Transplantation hépatique et grossesse

“…Des grossesses gémellaires ont également été rapportées [6], de même que des transplantations hépatiques réalisées chez des patientes enceintes et ayant permis la naissance d'enfants vivants [7].…”