2005
Successful Treatment of Recalcitrant Pemphigus Vulgaris and Pemphigus Vegetans With Etanercept and Carbon Dioxide Laser
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2005
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Cited by 65 publications
(29 citation statements)
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“…6 The use of etanercept in combination with carbon dioxide laser therapy to treat recalcitrant pemphigus vulgaris and pemphigus vegetans also has been described. 7 These observations, together with the use of etanercept, a soluble TNF receptor, in the patient described here, warrant further evaluation of its use in the treatment of immunobullous disorders. Financial support for the manuscript was provided by Amgen Inc and by Wyeth Research.…”
Section: Discussion
mentioning
confidence: 60%
“…6 The use of etanercept in combination with carbon dioxide laser therapy to treat recalcitrant pemphigus vulgaris and pemphigus vegetans also has been described. 7 These observations, together with the use of etanercept, a soluble TNF receptor, in the patient described here, warrant further evaluation of its use in the treatment of immunobullous disorders. Financial support for the manuscript was provided by Amgen Inc and by Wyeth Research.…”
Section: Discussion
mentioning
confidence: 60%
“…PV is an autoimmune skin and mucosal condition characterized by flaccid blisters and erosions, caused by autoantibodies, which target desmogleins 1, 3, 6, and 7 found in the keratinocytes [ 4 ]. The present-day approach to treat PV involves the use of systemic glucocorticosteroids, immunosuppressive medications such as azathioprine, mycophenolate mofetil, or cyclophosphamide and monoclonal antibodies such as rituximab [ 5 ].…”
Section: Discussion
mentioning
confidence: 99%
“…Therefore, adjuvant drugs e.g., azathioprine, cyclophosphamide, mycophenolate mofetil, cyclosporine, methotrexate, dapsone or retinoids are used in combination with the aim of having a steroid‐sparing action . In individual case reports of patients with recalcitrant pemphigus vegetans, extracorporeal photopheresis, rituximab and etanercept in combination with C0 2 laser therapy were applied …”
Section: Discussion
mentioning
confidence: 99%
