Successful treatment of familial congenital chylothorax by ligation of the thoracic duct: A case report

Dori, Leopoldini; Smaropoulos, Eleftherios; Tagarakis, Georgios I; Foroulis, Christophoros N.; Huang, Haidong; Bai, Chong; Hohenforst-Schmidt, Wolfgang; Tsikopoulos, George

doi:10.1016/j.rmcr.2017.03.017

Cited by 5 publications

(6 citation statements)

References 13 publications

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“…Medium and short-chain fatty acid bypass the lymph flow and directly absorb into the portal vein system [ 7 ]. In previously reported cases, death has been reported due to starvation; therefore, the mainstay for the treatment of severe cases should be intravenous nutrients in the present times that replace the deficient nutrients [ 8 ]. Parenteral feeding via a peripheral vein is recommended in infants with chylothorax to prevent superior vena cava thrombosis [ 7 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

“…In previously reported cases, death has been reported due to starvation; therefore, the mainstay for the treatment of severe cases should be intravenous nutrients in the present times that replace the deficient nutrients [ 8 ]. Parenteral feeding via a peripheral vein is recommended in infants with chylothorax to prevent superior vena cava thrombosis [ 7 , 8 ]. Surgery should be reserved as a last alternative until the trial of parenteral feeding fails to yield favorable outcomes [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

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Management of Spontaneous Chylothorax in a Neonate: A Medical Challenge

Ullah¹,

Rauf²,

Malik³

et al. 2021

Cureus

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Chylothorax or collection of lymphatic fluid in the pleural space is an exceedingly rare cause of pleural effusion and respiratory distress in neonates. In adults, prompt diagnosis and effective treatment regimen can aid in the resolution of chylothorax; however, in neonates treating the condition can be an onerous challenge for the pediatricians due to the rarity and perplexing clinical presentation. We elucidate a case of spontaneous chylothorax in a 15-day-old neonate who presented to us with respiratory distress, chest indrawing, and cyanosis for nine days. The prenatal and birth history of the patient were insignificant. The detailed laboratory and radiological assessment of the patient divulged a diagnosis of spontaneous chylothorax for which the patient was intubated. Unfortunately, the patient deteriorated and eventually expired on the 23rd postnatal day due to the complications of respiratory acidosis and hypoxemia.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Management of Spontaneous Chylothorax in a Neonate: A Medical Challenge

Ullah¹,

Rauf²,

Malik³

et al. 2021

Cureus

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“…One additional case reported a patient to have received octreotide for 151 days, resulting in resolution of the chylothorax 14. Other cases report the need for surgery to ligate the thoracic duct if conservative treatment fails, including one case of familial congenital chylothorax 15–17. The variability in presentation and severity mean there remains no consensus on best practice in management of congenital chylothorax.…”

Section: Discussionmentioning

confidence: 99%

Rare case of congenital chylothorax and challenges in its management

2019

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This case describes the difficulties faced in treating recurrent pleural effusions and diagnosing chylothorax in a preterm neonate. The mother of this case was one of the first neonates to undergo in utero pleural shunting for bilateral pleural effusions 30 years ago. She then presented with an antenatal diagnosis of fetal hydrops at 31+1 weeks gestation in her own pregnancy and her baby was delivered 3 days later due to concerns about fetal distress. The baby was clinically unstable with recurrent bilateral effusions which were extensively investigated and shown to be the result of congenital chylothorax of possible genetic origin. This case demonstrates the challenges of managing chylothorax in the newborn.

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“…According to Dori et al (2017), the chyle accumulation in the pleural area is known as chylothorax. In children, chylothorax is a relatively uncommon cause of pleural effusion, but it can result in severe respiratory morbidity, malnourishment, and immunodeficiency, which can cost more and cause more extended hospital stays (Dori et al, 2017;Krishnamurthy & Malhotra, 2017). The cause of chylothorax is either a disturbance or malfunction of the chyle flow via the thoracic duct or any of its branches.…”

Section: Introductionmentioning

confidence: 99%

Chylothorax: Approaches to Diagnosis and Treatment

Hari Nastiti,

Sekarsari,

Setyaningrum

et al. 2024

ijsh

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Chylothorax is a rare disease and epidemiologically is most commonly found in children. It can also result in severe respiratory morbidity such as pleural effusion and has a high mortality rate in children. Conservative treatment and consideration of surgical intervention may be warranted as the primary goal of chylothorax management is to remove fluid accumulation in the pleural cavity, avoid recurrence, treat associated problems, and find the underlying cause while maintaining optimal nutrition. We report two cases of chylothorax in children. Data were collected retrospectively from children diagnosed with chylothorax in the pediatric ward of RSUD Dr. Soetomo in 2022. This is a series of cases that includes two children diagnosed with chylothorax. case series involving two patients who underwent cardiac and congenital thoracic surgery and developed chylothorax. Patients receiving partial parenteral nutrition with MCT have improved drainage outcomes. After birth, thoracentesis closes the thoracic drainage, and life support is usually necessary for babies with chylothorax because they often have poor cardiopulmonary function

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Successful treatment of familial congenital chylothorax by ligation of the thoracic duct: A case report

Cited by 5 publications

References 13 publications

Management of Spontaneous Chylothorax in a Neonate: A Medical Challenge

Management of Spontaneous Chylothorax in a Neonate: A Medical Challenge

Rare case of congenital chylothorax and challenges in its management

Chylothorax: Approaches to Diagnosis and Treatment

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