Archives of Otolaryngology - Head and Neck Surgery
 1997
DOI: 10.1001/archotol.1997.01900010038005
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Successful Treatment of Esthesioneuroblastoma and Neuroendocrine Carcinoma With Combined Chemotherapy and Proton Radiation: Results in 9 Cases

Neil Bhattacharyya
1
,
Allan F. Thornton2,
M. P. Joseph3
et al.
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Cited by 115 publications

(102 citation statements)
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“…At least a partial response is reported in 60%–80% of patients with advanced SCC 11,13,14 . While results are less frequently reported for other pathologies, response rates seem to fall in a similar range 15–18 . In our cohort of all sinonasal malignancy that underwent IC, there was no significant difference in IC response based on tumor histology, although this analysis is limited by very small sample sizes in rarer histologies.…”
Section: Discussioncontrasting
confidence: 50%
“…11,13,14 While results are less frequently reported for other pathologies, response rates seem to fall in a similar range. [15][16][17][18] In our cohort of all sinonasal malignancy that underwent IC, there was no significant difference in IC response based on tumor histology, although this analysis is limited by very small sample sizes in rarer histologies. The benefits of IC may include decreased morbidity/toxicity of definitive treatment due to tumor response, including possible orbital preservation.…”
Section: Discussionmentioning
confidence: 72%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…At least a partial response is reported in 60%–80% of patients with advanced SCC 11,13,14 . While results are less frequently reported for other pathologies, response rates seem to fall in a similar range 15–18 . In our cohort of all sinonasal malignancy that underwent IC, there was no significant difference in IC response based on tumor histology, although this analysis is limited by very small sample sizes in rarer histologies.…”
Section: Discussioncontrasting
confidence: 50%
“…11,13,14 While results are less frequently reported for other pathologies, response rates seem to fall in a similar range. [15][16][17][18] In our cohort of all sinonasal malignancy that underwent IC, there was no significant difference in IC response based on tumor histology, although this analysis is limited by very small sample sizes in rarer histologies. The benefits of IC may include decreased morbidity/toxicity of definitive treatment due to tumor response, including possible orbital preservation.…”
Section: Discussionmentioning
confidence: 72%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…A combination of cyclophosphamide, vincristine, and doxorubicin was used by some institutions 42 while others considered the use of cisplatin based regimens. Cisplatin combined with etoposide seems to be the most popular regimen used for ONB 46,47 . In our study 43 patients received chemotherapy.…”
Section: Discussionmentioning
confidence: 86%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Although early reports on chemotherapy in ENB focused on patients with recurrent or metastatic disease, adjuvant chemotherapy is now commonly used for patients with advanced locoregional disease. Numerous protocols have been published in literature presenting favourable results with cisplatin based chemotherapy [12,[19][20][21]. Two of our patients received post operative chemotherapy after RT, one having systemic metastasis and the other with regional recurrence.…”
Section: Discussionmentioning
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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