Successful pain control with add-on methadone for refractory neuropathic pain due to radiation necrosis in pontine metastatic lesion: A case report
Fumio Kurosaki,
Ayako Takigami,
Mitsue Takeuchi
et al.
Abstract:Background
Central pain, characterized by neuropathic pain, can manifest due to injury to the superior spinothalamic tract. The brainstem, including sensory and motor pathways as well as cranial nerve nuclei, necessitates early intervention when affected by cancer metastasis. Although stereotactic radiosurgery (SRS) is commonly employed for the treatment of brain metastasis, it poses risks of late complications like radiation necrosis (RN). RN exacerbates the progression of brain lesions within the irradiated… Show more
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