2016
DOI: 10.1007/s00268-016-3743-3
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Abstract: The width between the tumor and resection margin does not affect the recurrence after R0 sublobar resection in patients with clinical N0 GGO-predominant lung cancer ≤3 cm. By contrast, margin width is a significant risk factor for recurrence after sublobar resection in patients with clinical N0 solid-predominant lung cancer.

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Cited by 31 publications
(23 citation statements)
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References 29 publications
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“…In the study by Moon et al, [41] there was no recurrence in GGO-predominant tumors after sublobar resection, and this was not influenced by margin-distance. However, for solid-predominant tumors, the 5-year recurrencefree survival after sublobar resection according to margin-distances of less than 5 mm and more than 5 mm were 24.2% and 79.6 %, respectively (P = 0.001).…”
Section: Pulmonary Wedge Resection For Ggo Predominant Lesionsmentioning
confidence: 77%
“…In the study by Moon et al, [41] there was no recurrence in GGO-predominant tumors after sublobar resection, and this was not influenced by margin-distance. However, for solid-predominant tumors, the 5-year recurrencefree survival after sublobar resection according to margin-distances of less than 5 mm and more than 5 mm were 24.2% and 79.6 %, respectively (P = 0.001).…”
Section: Pulmonary Wedge Resection For Ggo Predominant Lesionsmentioning
confidence: 77%
“…Sublobar resections have in fact been reported as being oncologically equivalent to major anatomical resections in non-invasive and minimally invasive tumours. 2,3 However, tumour invasiveness is hard to be determined at preoperative or intraoperative assessment, since significant limitations exist in the definition of tumour invasiveness in histological specimens obtained by needle biopsy and with intraoperative frozen section. 5,6 Thus, the identification of CT and PET features of non-invasive and invasive tumours may be essential to differentiate invasive and non-invasive lesions, in order to select the optimal surgical treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Different surgical approaches have therefore been proposed according to the histological features of the tumour, with sublobar resection as a possible treatment option for adenocarcinoma in situ and minimally-invasive adenocarcinoma. 2,3 Conversely, major resection is still considered the treatment of choice of early-stage invasive adenocarcinomas. 4 Hence, the identification of pre-operative parameters that allow differentiating neoplastic lesions according to tumour invasiveness is crucial for the planning of surgical treatment.…”
Section: Introductionmentioning
confidence: 99%
“…In the case of lung cancer presenting as GGO on CT scan, the prognosis of sublobar resection is known to be acceptable. There are many studies that support these results [2][3][4][5]. In addition to the increasing frequency of sublobar resection of GGO-dominant tumors, studies have been conducted to demonstrate the e cacy of sublobar resection for solid-dominant tumors of 2 cm or less.…”
Section: Introductionmentioning
confidence: 90%