Subjective Response to Antipsychotic Drugs

Attitude towards second‐generation antipsychotics among patients with schizophrenia and their relatives

“…The majority of studies have found positive symptoms to have the greatest adverse effect on attitudes (Garcia Cabeza et al , ; Hofer et al , ; Freudenreich et al , ; Lambert et al , ; Adewuya et al , ; Kuroda et al , ; Rocca et al , ; Rossi et al , ; Mohamed et al , ; Haq et al , ), whereas some have also found a link between negative attitudes and overall levels of symptoms, general psychopathology, or negative and depressive symptoms (Freudenreich et al , ; Adewuya et al , ; Rocca et al , ; Mohamed et al , ) . The finding that patients with higher side effect burden tended to have more negative attitudes towards the medication is in agreement with several previous studies (Van Putten et al , ; Hogan and Awad, ; Hofer et al , ; Lambert et al , ; Adewuya et al , ; Kuroda et al , ). However, others have failed to demonstrate an association between side effects and attitudes (Garcia Cabeza et al , ; Ritsner et al , ; Freudenreich et al , ; Day et al , ; Hofer et al , ).…”

Reasons for Quitting Serotonin Reuptake Inhibitor Therapy: Paradoxical Psychological Side Effects and Patient Satisfaction

“…Nonetheless, these experiences were reported to affect decisions to stop taking the medication in a number of respondents in our sample. This is in accord with other studies of adherence and subjective responses to medication [16, 17, 18, 19]. …”

Attitude towards antipsychotics among out‐patients with schizophrenia in Nigeria

“…Our study showed that dyskinesia was significantly associated with poor attitude towards antipsychotic drugs among our patients with schizophrenia. This is in agreement with other studies that have found a significant relationship between extra‐pyramidal side‐effect and attitude towards antipsychotic medication (32, 33) and in disagreement with other studies that found no such association (10, 13, 34). Many patients experience antipsychotic drugs as unpleasant and something they would prefer to avoid it (35).…”