Subcutaneous granuloma annulare of the penis in 2 adolescents

Necrobiosis Lipoidica of the Glans Penis

“…A number of cases of GA located only on the penis have been reported (8)(9)(10)(11). All of these cases bore marked clinical differences from the patients who had NL of the glans penis.…”

“…The key clinical feature was the presence of firm, asymptomatic nodules on the shaft of the penis that did not ulcerate and did not leave scars. In some cases, spontaneous remission and remission after skin biopsy was reported (8)(9)(10)(11).…”

“…Mucin was present in the majority of cases (8,11), in one case with giant cells (9). In most cases, the granulomas were located in the mid/deep dermis and subcutaneous tissue and were diagnosed as deep or subcutaneous GA (8,10).…”

Granuloma annulare of the penis in a seven-year-old boy

“…Specific to the paediatric population, differential diagnoses of penile GA include posttraumatic, necrobiosis lipodica [12], epithelial cysts, ringworm and rheumatoid nodules [13]. In adults, Peyronie's disease, condylomata, penile carcinoma, syphilis, sarcoidosis, dermatofibroma and lichen planus should also be considered as possibilities.…”

“…Patients frequently seek treatment for cosmetic reasons owing to the anatomical location of the lesion [3]. Treatment consists of surgical excision to confirm the diagnosis [13]. The biopsy process itself may be curative [15] and result in remission.…”