Subcutaneous abscess due to empyema necessitans caused by Porphyromonas gingivalis in a patient with periodontitis

Tanaka, Akane; Kogami, Mariko; Nagatomo, Yoko; Takeda, Yukihisa; Kanzawa, Hiroya; Kawaguchi, Yohei; Ono, Shotaro; Furukawa, Kinya; Nakamura, Hiroyuki; Aoshiba, Kazutetsu

doi:10.1016/j.idcr.2022.e01458

Cited by 9 publications

(9 citation statements)

References 15 publications

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“…Pyopneumothorax with bronchopleural fistula from P. gingivalis is very rare. A case of empyema and subcutaneous abscess caused by P. gingivalis infection was reported 14 . To the best of our knowledge, this case report is the first case of pyopneumothorax with bronchopleural fistula caused by P. gingivalis .…”

Section: Discussionmentioning

confidence: 75%

Pyopneumothorax with bronchopleural fistula due to pulmonary infection caused by Porphyromonas gingivalis in a patient with periodontitis

Sha,

Shao,

et al. 2023

Clinical Respiratory J

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Pyopneumothorax with bronchopleural fistula is a rare complication of lung infection. We herein report a case of pyopneumothorax with bronchopleural fistula caused by Porphyromonas gingivalis infection, a common pathogenic pathogen of periodontitis, in a 49‐year‐old man with periodontitis. The patient was admitted with respiratory failure. Pleural puncture yielded a lot of gas continually and foul‐smelling light brown pus, which was found to be caused due to infection with P. gingivalis by the metagenomic next generation sequencing (mNGS) and anaerobic culture.

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Section: Discussionmentioning

confidence: 75%

Pyopneumothorax with bronchopleural fistula due to pulmonary infection caused by Porphyromonas gingivalis in a patient with periodontitis

Sha,

Shao,

et al. 2023

Clinical Respiratory J

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“…Brain abscesses caused by P. gingivalis have been reported in several studies ( 3 – 6 ). Recently, Tanaka et al ( 8 ) reported the first case of chest subcutaneous abscess caused by P. gingivalis . To the best of our knowledge, muscle abscesses and brain abscesses in the same patient caused by P. gingivalis have not been reported.…”

Section: Discussionmentioning

confidence: 99%

“…However, we did confirm that there were few if any aerobes in these samples. Tanaka et al ( 8 ) reported a case of empyema necessitans that presented as a subcutaneous chest wall abscess caused by P. gingivalis . In this case, percutaneous puncture of the subcutaneous abscess was performed, and foul-smelling chocolate-colored pus was aspirated.…”

Section: Discussionmentioning

confidence: 99%

Case report:Multiple abscesses caused by Porphyromonas gingivalis diagnosed by metagenomic next-generation sequencing

Zhang¹,

Zhu²,

Wan

2023

Front. Med.

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BackgroundExtraoral infection by Porphyromonas gingivalis (P. gingivalis) is extremely rare and challenging to diagnose because the fastidious pathogen is difficult to culture by traditional methods. We report the first case of a patient with multiple abscesses in muscles and the brain with dura empyema due to P. gingivalis, which was diagnosed by metagenomic next-generation sequencing (mNGS).Case presentationA 65-year-old male patient was admitted to our hospital for multiple lumps in his body. Brain magnetic resonance imaging (MRI) and lower-limb computed tomography (CT) revealed multiple abscesses in the brain and muscles. A diagnosis of P. gingivalis infection was made based on mNGS tests of blood, cerebrospinal fluid (CSF), and pus samples, as the traditional bacterial culture of these samples showed negative results. Target antibiotic therapy with meropenem and metronidazole was administered, and CT-guided percutaneous catheter drainage of abscesses in both thighs was performed. The size of muscle abscesses reduced significantly and neurological function improved. The patient was followed up for 4 months. No abscesses re-appeared, and the remaining abscesses in his backside and both legs were completely absorbed. He can speak fluently and walk around freely without any neurological deficits.ConclusionMetagenomic next-generation sequencing is helpful for early diagnosis and subsequent treatment of P. gingivalis-associated multiple abscesses.

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“…5 Empyema necessitans can also be a complication of poor dental health, including periodontitis. 6 Cases may also be polymicrobial in nature. 7 Patients may manifest disease with fever and severe systemic toxicity, although the evolution and presentation can also be indolent in nature.…”

Section: Discussionmentioning

confidence: 99%

“…1 The infectious etiology most classically associated with this diagnosis is Mycobacterium tuberculosis , 2 although many pathogens have been described (Table 1). 3-7 These etiologies include the endemic mycoses histoplasmosis, blastomycosis, and coccidioidomycosis. 4 Less common etiologies can include parasitic infections such as Paragonimus westermani .…”

Section: Discussionmentioning

confidence: 99%

A Rapidly Expanding Chest Wall Mass in an Adolescent With COVID-19

Klair,

Ireland,

Schleiss

2023

Clin Pediatr (Phila)

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Subcutaneous abscess due to empyema necessitans caused by Porphyromonas gingivalis in a patient with periodontitis

Cited by 9 publications

References 15 publications

Pyopneumothorax with bronchopleural fistula due to pulmonary infection caused by Porphyromonas gingivalis in a patient with periodontitis

Pyopneumothorax with bronchopleural fistula due to pulmonary infection caused by Porphyromonas gingivalis in a patient with periodontitis

Case report:Multiple abscesses caused by Porphyromonas gingivalis diagnosed by metagenomic next-generation sequencing

A Rapidly Expanding Chest Wall Mass in an Adolescent With COVID-19

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