2015
DOI: 10.1590/1678-4162-8057
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Abstract: ABSTRACTTo test clinically whether a small dose of ifenprodil can enhance the anti-hyperalgesic effect of ketamine in dogs, a prospective randomized cross-over study was done with eight mongrel dogs (weighing 16.9 ± 3.7kg). Animals received two distinct treatments: ketamine (0.3mg kg-1; KT) and an ifenprodil plus ketamine combination (0.03mg kg -1 and 0.3mg kg -1 , respectively; IKT). Dogs were anesthetized with propofol (5mg kg -1 intravenously) and a subarachnoid needle was placed between the 5 th and 6 th …

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