volume 7, issue 1, P39-58 1973
DOI: 10.1002/jbm.820070104
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Abstract: SummaryA group of 12 materials was evaluated for tissue compatibility via a sequential histopathologic evaluation of the rabbit muscle response to the implanted materials. Tissue samples were obtained daily for 7 days and weekly for 12 weeks to follow the time course of the response. Some cytotoxic samples revealed a rapid and marked response of relatively short duration, whereas others tended to produce a sustained or a long-term, intermittent inflammatory and/or necrotic response. These effects also demonst…

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