Su1320 Prevalence of Impaired Muscle Strength in an IBD Outpatient Cohort

Spooren, Corinne; Pierik, Marie J.; Heuvel, Tim van den; Koning, Erwin De; Mechelen, Zoe N. van; Masclee, Ad; Jonkers, Daisy

doi:10.1016/s0016-5085(15)31591-2

Cited by 1 publication

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“…Anaerobic threshold, muscle strength, and heart rate recovery are lower in IBD populations, although the mechanism is not clear. 53 – 58 One study of 29 CD patients who had small bowel surgery and proctocolectomy found that all patients had reduced exercise capacity, but the degree of reduction was greater in those with greater lengths of small bowel resected. 55 Interestingly, 72 UC patients who underwent ‘curative’ proctocolectomy had normal exercise capacity 12 months after ileal pouch-anal anastomosis.…”

Section: Introductionmentioning

confidence: 99%

“…Overall, these data demonstrate that exercise capacity may be reduced in IBD patients. 53 – 59 Despite theoretical concerns and conflicting data from animal models, moderate- to low-intensity exercise appears to be safe with minimal risk of symptom exacerbation when prospectively studied in patients with quiescent to moderately active disease. Very limited data suggest that even high-intensity exercise may be safe in selected IBD patients.…”

Section: Introductionmentioning

confidence: 99%

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Exercise in patients with inflammatory bowel diseases: current perspectives

Engels¹,

Cross²,

Long³

2017

CEG

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Inflammatory bowel diseases (IBDs), including both Crohn’s disease (CD) and ulcerative colitis (UC), are chronic autoimmune diseases. Both CD and UC have relapsing and remitting courses. Although effective medical treatments exist for these chronic conditions, some patients do not respond to these traditional therapies. Patients are often left frustrated with incomplete resolution of symptoms and seek alternative or complementary forms of therapy. Patients often search for modifiable factors that could improve their symptoms or help them to maintain periods of remission. In this review, we examine both the published evidence on the benefits of exercise clinically and the pathophysiological changes associated with exercise. We then describe data on exercise patterns in patients with IBDs, potential barriers to exercise in IBDs, and the role of exercise in the development and course of IBDs. While some data support physical activity as having a protective role in the development of IBDs, the findings have not been robust. Importantly, studies of exercise in patients with mild-to-moderate IBD activity show no danger of disease or symptom exacerbation. Exercise has theoretical benefits on the immune response, and the limited available data suggest that exercise may improve disease activity, quality of life, bone mineral density, and fatigue levels in patients with IBDs. Overall, exercise is safe and probably beneficial in patients with IBDs. Evidence supporting specific exercise recommendations, including aspects such as duration and heart rate targets, is needed in order to better counsel patients with IBDs.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%