Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.12.080 View full text
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Feng Wei, Bo Shen, Mingjie Chen, Yingxian Zhao

Abstract: There is a trapping effect on the solute in the simulated moving bed (SMB) with solvent gradient. As the eluotropic strength of the liquid in zone II (between the extract-port and feed-port) is higher than that in zone III (between the feed-port and the raffinate-port), the solute can move forward in zone II but backward in zone III to be trapped in the two zones consequently. On this basis, a pseudo-SMB was proposed to separate the medium retained solute from a ternary mixture by selectively trapping the medi…

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