Study of the formulation optimization and reusability of a MAGAT gel dosimeter

Resende, Thiago Dias; Lizar, Jéssica Caroline; Santos, Fred Muller dos; Borges, Leandro Federiche; Pavoni, Juliana Fernandes

doi:10.1016/j.ejmp.2019.05.018

Cited by 4 publications

(5 citation statements)

References 35 publications

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“…The MAGAT gel phantom after the star shot irradiation in the MR‐Linac was scanned using the same device without any change in the setup. Signal of polymer gels continues to increase up to 24 h after the irradiation, improving a contrast‐to‐noise ratio (i.e., high dose response) 10,26 . However, we investigate only geometrical information so that a conversion into dose is not required.…”

Section: Methodsmentioning

confidence: 99%

“…Signal of polymer gels continues to increase up to 24 h after the irradiation, improving a contrast‐to‐noise ratio (i.e., high dose response). 10 , 26 However, we investigate only geometrical information so that a conversion into dose is not required. In the previous study by Dorsch et al., 10 the PAGAT gel was imaged directly after the irradiation.…”

Section: Methodsmentioning

confidence: 99%

“…The gel solution was placed in the customized acrylic phantom and stored in a 4°C refrigerator for 24 h prior to an irradiation. The gel was left at room temperature for 30 min before irradiation 26 …”

Section: Methodsmentioning

confidence: 99%

“…The gel was left at room temperature for 30 min before irradiation. 26 Figure 1 shows the basic structure and external form of the acrylic phantom fabricated in this study as well as the MR image. The phantom had a length of 19.5 cm in length and diameter of 15 cm.…”

Section: Fabrication Of Magat Gel Phantommentioning

confidence: 99%

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3D star shot analysis using MAGAT gel dosimeter for integrated imaging and radiation isocenter verification of MR‐Linac system

Kim

Shin

et al. 2022

J Applied Clin Med Phys

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This study aims to investigate a star shot analysis using a threedimensional (3D) gel dosimeter for the imaging and radiation isocenter verification of a magnetic resonance linear accelerator (MR-Linac). Methods: A mixture of methacrylic acid, gelatin, and tetrakis (hydroxymethyl) phosphonium chloride, called MAGAT gel, was fabricated. One MAGAT gel for each Linac and MR-Linac was irradiated under six gantry angles. A 6 MV photon beam of Linac and a 6 MV flattening filter free beam of MR-Linac were delivered to two MAGAT gels and EBT3 films. MR images were acquired by MR-Linac with a clinical sequence (i.e., TrueFISP). The 3D star shot analysis for seven consecutive slices of the MR images with TrueFISP was performed. The 2D star shot analysis for the central plane of the gel was compared to the results from the EBT3 films. The radius of isocircle (IC r ) and the distance between the center of the circle and the center marked on the image (IC d ) were evaluated. Results: For MR-Linac with MAGAT gel measurements, IC d at the central plane was 0.46 mm for TrueFISP. Compared to EBT3 film measurements, the differences in IC d and IC r for both Linac and MR-Linac were within 0.11 and 0.13 mm, respectively. For the 3D analysis, seven consecutive slices of TrueFISP images were analyzed and the maximum radii of isocircles (IC r_max ) were 0.18 mm for Linac and 0.73 mm for MR-Linac. The tilting angles of radiation axis were 0.31 • for Linac and 0.10 • for MR-Linac. Conclusion:The accuracy of 3D star shot analysis using MAGAT gel was comparable to that of EBT3 film, having a capability for integrated analysis for imaging isocenter and radiation isocenter.3D star shot analysis using MAGAT gel can provide 3D information of radiation isocenter, suggesting a quantitative extent of gantry-tilting.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Fabrication Of Magat Gel Phantommentioning

confidence: 99%

See 2 more Smart Citations

3D star shot analysis using MAGAT gel dosimeter for integrated imaging and radiation isocenter verification of MR‐Linac system

Kim

Shin

et al. 2022

J Applied Clin Med Phys

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“…New investigations of polymeric formulations were proposed, such as the MAGAT (Methacrylic Acid Gelatin And Tetrakis (hydroxymethyl) phosphonium chloride), also composed of a gel matrix made of water and gelatin and some monomers. Some investigations have reported its characteristics as tissue-equivalent highest dosimeter sensitivity [20,21,[27][28][29], improving better than MAGIC polymer gels [22,30].…”

Section: Introductionmentioning

confidence: 99%

Relative dose-response from solid-state and gel dosimeters through Monte Carlo simulations

2022

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The present work compared the relative absorbed dose of some dosimetric materials, for energies of 250 kV and 6 MV, using PENELOPE and MNCPX codes. The composition of each material GD-301, TLD-100, MAGIC, and MAGAT were simulated and disposed of in a phantom filled with water following reference conditions recommended by the TRS-398 protocol. Percentage depth dose was used as a parameter of comparison. Since the obtained results with both codes were found a maximum difference of up to 2 % when compared the water material with experimental data before 6cm were found to a maximum difference of up to 2.2% for 6 MV and 5.5 % for 250 kV. Ratios between simulated PPD and experimental PDD values showed a maximum difference in the build-up region, for 6 MV, due to highsensitivityive from the incident fluency in the simulated and experimental conditions. The ratios for 250 kV showed significant differences from the simulated solid-state rather than gel dosimeters, due to its low energy, depth angular dependence from the solid-state dosimeter, as corroborating by literature. Even the differences showed for both codes, especially for lower energy, due to cross-the section database that implied the interaction probability for each Monte Carlo code, this method has been widely used to model radiation transport in several applications in medical physics, especially in dosimetry.

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Optical investigation of MAGAT polymer gel dosimeter embedded with methylene blue dye and zinc oxide nanoparticles using UV/Vis spectrometry pre- and post-irradiation of 6MV photon beam

Al-Asady,

Razak,

Zin

et al. 2024

Polym. Bull.

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Study of the formulation optimization and reusability of a MAGAT gel dosimeter

Cited by 4 publications

References 35 publications

3D star shot analysis using MAGAT gel dosimeter for integrated imaging and radiation isocenter verification of MR‐Linac system

3D star shot analysis using MAGAT gel dosimeter for integrated imaging and radiation isocenter verification of MR‐Linac system

Relative dose-response from solid-state and gel dosimeters through Monte Carlo simulations

Optical investigation of MAGAT polymer gel dosimeter embedded with methylene blue dye and zinc oxide nanoparticles using UV/Vis spectrometry pre- and post-irradiation of 6MV photon beam

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